Protein Info for DZA65_RS04720 in Dickeya dianthicola ME23

Annotation: type II toxin-antitoxin system antitoxin CcdA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 72 PF07362: CcdA" amino acids 2 to 72 (71 residues), 99.4 bits, see alignment E=6e-33

Best Hits

Swiss-Prot: 67% identical to CCDA_ECO57: Antitoxin CcdA (ccdA) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 93% identity to dda:Dd703_3039)

Predicted SEED Role

"CcdA protein (antitoxin to CcdB)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CA80 at UniProt or InterPro

Protein Sequence (72 amino acids)

>DZA65_RS04720 type II toxin-antitoxin system antitoxin CcdA (Dickeya dianthicola ME23)
MKHRVSVTVDKDNYQILSAAGVNISGLVNDAIGKEARRIKAEQWKKENREGMEEVARFIA
QNGSFADENRNW