Protein Info for DZA65_RS04500 in Dickeya dianthicola ME23

Annotation: carbohydrate ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 275 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details transmembrane" amino acids 74 to 94 (21 residues), see Phobius details amino acids 106 to 128 (23 residues), see Phobius details amino acids 142 to 162 (21 residues), see Phobius details amino acids 186 to 208 (23 residues), see Phobius details amino acids 241 to 266 (26 residues), see Phobius details PF00528: BPD_transp_1" amino acids 86 to 269 (184 residues), 68.2 bits, see alignment E=3.9e-23

Best Hits

KEGG orthology group: K02026, multiple sugar transport system permease protein (inferred from 96% identity to ddd:Dda3937_01455)

MetaCyc: 34% identical to ABC-type 3-(6-sulfo-alpha-D-quinovosyl)-sn-glycerol transporter permease subunit (Agrobacterium fabrum)
7.5.2.M1 [EC: 7.5.2.M1]

Predicted SEED Role

"Various polyols ABC transporter, permease component 2" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.M1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4D2T1 at UniProt or InterPro

Protein Sequence (275 amino acids)

>DZA65_RS04500 carbohydrate ABC transporter permease (Dickeya dianthicola ME23)
MRLPYWLTALRALALTVALLFFTLPILWMAATAFKSTAEFASLSSPFWPQQWTLTHLKSL
LDSGVGARLFNTLRVAAGATALSLLTGFLAAYTLARHRFPARLDSLFLLLVLLVKMMPPM
VVAIPLYSLLKSLHLLNSLTGLMLAYQVYTLPFCIWMLLSFIRDVPLSLEEAAAMDGAGL
WRRLRYIVLPVCAPGLVATAIFTLIMAWNEFLFALLYLQTPQQFTLPLFIANFMTENQIY
WGELMSIGLLSSLPVLLVAGFVQRYLLRGFAVSQK