Protein Info for DZA65_RS04305 in Dickeya dianthicola ME23

Annotation: cytosine permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 431 transmembrane" amino acids 20 to 46 (27 residues), see Phobius details amino acids 52 to 73 (22 residues), see Phobius details amino acids 93 to 111 (19 residues), see Phobius details amino acids 131 to 152 (22 residues), see Phobius details amino acids 159 to 181 (23 residues), see Phobius details amino acids 193 to 215 (23 residues), see Phobius details amino acids 227 to 250 (24 residues), see Phobius details amino acids 259 to 279 (21 residues), see Phobius details amino acids 310 to 327 (18 residues), see Phobius details amino acids 333 to 355 (23 residues), see Phobius details amino acids 376 to 394 (19 residues), see Phobius details amino acids 400 to 418 (19 residues), see Phobius details PF02133: Transp_cyt_pur" amino acids 21 to 398 (378 residues), 86 bits, see alignment E=1.3e-28

Best Hits

KEGG orthology group: K10974, cytosine permease (inferred from 94% identity to ddd:Dda3937_01412)

Predicted SEED Role

"Cytosine permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XUF8 at UniProt or InterPro

Protein Sequence (431 amino acids)

>DZA65_RS04305 cytosine permease (Dickeya dianthicola ME23)
MESIDDYPVSRVPTSVRLPFFNVALVHIGMLTALDQFMLGAVLGHAMTLGEAFLAIAIGS
AIFGVVTLGLGYAGMKEGLSGSLLARWCGFGRMGAVFIGAIIAVSLLGWFGVQNAVFAKS
LNFALGDRLGFGWSAALSGCALTLLVTFGFSALRYTARIAVPLFIMVVGYISTMTLTGHN
LTDLLQKSVSGEAISVSAGATMVVGGCIVASLITPDMTRYSRRGRHVFWITISSVIIGEF
IVNGLAILIARALNTADIVTIMSQTAGGIGLITVIFSTLRINDINLYSSSLGIANAVEGI
TGRKLSYKSITLLIGFIGTFLSVIGILDRFVDFLTLLGVFFPPVIGVMLVDYYILRTSRR
LLDESRQHGELPEAGNTPDVGWSAIIASLVGSALGLFTDWGIPALNSLLAASLLYWLIKA
RLPAVKSIQGR