Protein Info for DZA65_RS03625 in Dickeya dianthicola ME23

Annotation: polysaccharide biosynthesis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 627 transmembrane" amino acids 21 to 41 (21 residues), see Phobius details amino acids 48 to 69 (22 residues), see Phobius details amino acids 83 to 108 (26 residues), see Phobius details amino acids 115 to 135 (21 residues), see Phobius details PF01370: Epimerase" amino acids 284 to 505 (222 residues), 62.8 bits, see alignment E=1e-20 PF02719: Polysacc_synt_2" amino acids 284 to 578 (295 residues), 410.5 bits, see alignment E=1.1e-126 PF04321: RmlD_sub_bind" amino acids 284 to 457 (174 residues), 32.2 bits, see alignment E=1.8e-11 PF16363: GDP_Man_Dehyd" amino acids 285 to 412 (128 residues), 41.5 bits, see alignment E=3.6e-14

Best Hits

KEGG orthology group: None (inferred from 96% identity to ddd:Dda3937_02274)

Predicted SEED Role

"UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.-)" in subsystem N-linked Glycosylation in Bacteria (EC 4.2.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.2.1.-

Use Curated BLAST to search for 4.2.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XU33 at UniProt or InterPro

Protein Sequence (627 amino acids)

>DZA65_RS03625 polysaccharide biosynthesis protein (Dickeya dianthicola ME23)
MFKPIPFLLSAERRNKRIMTVFYDVFAIVVSLYLAVAVRLGTMDFPVGYAEIASVLVTLS
ITLLVFIRCGMYRAVLRYMMLPAMGYVFLSVILSAISLALSGFFFQSFVPRSVPFIYAGL
ATLALGSPRVLIRTFYYHYYKRQKPNVFIYGAGATGRDLIYSLIQGDEFHPVVVLDDDEK
KIGQIICGIRVHHSSEFEKLKPLYQPVKLLLAINNIKKGLRLRLLEKLSHWPIEVQSVPS
VEDIAAGKAIATEIRDLDVADLLGREAVDPDKQLMSKNITGKSVMITGAGGSIGSELCRQ
ILTQHPHTLVLFELNEYNLYTIDQELQGIKKRLLLDTKIVAALGSVQKQNRIQKLIRAYQ
VETIYHAAAYKHVPLVEDNVIEGIRNNVFGTLACAESAIAEGVRNFTLISTDKAVRPTNI
MGTSKRMAELILQALAERQNQTTFTMVRFGNVLGSSGSVVPLFKKQIRQGGPVTVTHPDI
TRYFMLIPEAAQLVVQAGAMGINGQVFVLDMGEPVKILDLARRMINLMGMKGYIEGYGEE
GDIVIKFTGLRPGEKLYEELLIGENVEGTSHPRIMTAQEEKLSWQEMEQLLQQLDKSCHD
YDVGNIRKILLEAPTGYAPTANKCQKD