Protein Info for DZA65_RS03480 in Dickeya dianthicola ME23

Annotation: MHS family MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 transmembrane" amino acids 29 to 54 (26 residues), see Phobius details amino acids 65 to 86 (22 residues), see Phobius details amino acids 96 to 115 (20 residues), see Phobius details amino acids 123 to 148 (26 residues), see Phobius details amino acids 168 to 188 (21 residues), see Phobius details amino acids 198 to 218 (21 residues), see Phobius details amino acids 251 to 271 (21 residues), see Phobius details amino acids 291 to 313 (23 residues), see Phobius details amino acids 322 to 340 (19 residues), see Phobius details amino acids 347 to 370 (24 residues), see Phobius details amino acids 385 to 405 (21 residues), see Phobius details amino acids 411 to 431 (21 residues), see Phobius details PF00083: Sugar_tr" amino acids 24 to 230 (207 residues), 89.1 bits, see alignment E=3.2e-29 amino acids 271 to 440 (170 residues), 39.6 bits, see alignment E=3.3e-14 PF07690: MFS_1" amino acids 29 to 283 (255 residues), 61.9 bits, see alignment E=5.3e-21 amino acids 284 to 437 (154 residues), 51.2 bits, see alignment E=9.3e-18 TIGR00883: MFS transporter, metabolite:H+ symporter (MHS) family protein" amino acids 31 to 425 (395 residues), 492.3 bits, see alignment E=5.9e-152

Best Hits

Swiss-Prot: 81% identical to YHJE_ECOLI: Inner membrane metabolite transport protein YhjE (yhjE) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 98% identity to ddd:Dda3937_02298)

Predicted SEED Role

"Inner membrane metabolite transport protein YhjE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CG54 at UniProt or InterPro

Protein Sequence (441 amino acids)

>DZA65_RS03480 MHS family MFS transporter (Dickeya dianthicola ME23)
MQASISSTIDTQTPDAPVNSRNKVVVASLIGTAIEFFDFYIYATAAVLIFPHIFFPQGDA
TAATLQSLATFAIAFVARPIGSALFGHFGDRVGRKVTLVASLLTMGISTVLIGLLPSYET
IGVLAPLLLALARFGQGLGLGGEWGGAALLATENAPAHKRALYGSFPQLGAPIGFFFANA
TFLLLSWVMTNEQFMSWGWRVPFIASAVLVIIGLYVRVSLHETPVFAKVAKEGKQVRVPL
GTLLSKHVKATILGTFIMLATYTLFYIMTVYSMTYGTTPAPAGLGIPRNNFLWMLMVAVI
GFGLMIPVAGYLADAVGRRKTMITVTCIMLVFAMTFPSLLGSGNQTLIMAFLVCGLSLMG
LTFGPMGALLPELFPTEVRYTGASFSYNVSSILGASVAPYIAAWLTSHYGLFYVGVYLAA
MASLTLTALLLTKETRHQSLG