Protein Info for DZA65_RS02635 in Dickeya dianthicola ME23

Annotation: MHS family MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 433 transmembrane" amino acids 43 to 54 (12 residues), see Phobius details amino acids 60 to 79 (20 residues), see Phobius details amino acids 95 to 116 (22 residues), see Phobius details amino acids 126 to 150 (25 residues), see Phobius details amino acids 168 to 190 (23 residues), see Phobius details amino acids 196 to 215 (20 residues), see Phobius details amino acids 261 to 279 (19 residues), see Phobius details amino acids 285 to 307 (23 residues), see Phobius details amino acids 316 to 334 (19 residues), see Phobius details amino acids 340 to 359 (20 residues), see Phobius details amino acids 380 to 401 (22 residues), see Phobius details amino acids 407 to 428 (22 residues), see Phobius details PF00083: Sugar_tr" amino acids 26 to 235 (210 residues), 76 bits, see alignment E=3e-25 amino acids 232 to 432 (201 residues), 37.2 bits, see alignment E=1.7e-13 PF07690: MFS_1" amino acids 63 to 394 (332 residues), 105.5 bits, see alignment E=3e-34

Best Hits

KEGG orthology group: None (inferred from 84% identity to dda:Dd703_3446)

Predicted SEED Role

"L-Proline/Glycine betaine transporter ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4D716 at UniProt or InterPro

Protein Sequence (433 amino acids)

>DZA65_RS02635 MHS family MFS transporter (Dickeya dianthicola ME23)
MTMSLHAETPAHEQPSAVQTSRLAAASSIGTALEWYDFTVYNLMAALVFNHVFFPSFDPL
VGTILAFSTYAVGYVSRPVGGLIFGHLGDVLGRRFVLVTTLVIMGVTTAMMGLLPGYAQW
GIWSPILLVSLRFMQGVALGGEWAGAVLLSMEHGKPHQRGRNASFAQVGPSCGTLIGTGF
ITLITLLLSPSQFLDWGWRVPFLLSLVLVVFGLWLRRGVGETPAFLALEHQKKHREAPLK
TVFGDHLRALLIAGGARIGSDVLYALVVVFTLTYVTTVLQLPRPLALTATMLGAVANVIA
VPLFGILSDRLGRRPVYLGGAIAAIVWAFVFFMLLDVAQPLAICVAVVVGLIIHAAMYGP
QAAFVTEQFPTRVRYAGSSLAYTLAGIVGGGFAPLVITSLFRSWNSTLAISLYVCLALLV
TCLAVFCARETAH