Protein Info for DZA65_RS01940 in Dickeya dianthicola ME23

Annotation: circularly permuted type 2 ATP-grasp protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 479 PF04174: CP_ATPgrasp_1" amino acids 78 to 407 (330 residues), 498.2 bits, see alignment E=1e-153 PF14403: CP_ATPgrasp_2" amino acids 78 to 451 (374 residues), 543.5 bits, see alignment E=2.6e-167

Best Hits

Swiss-Prot: 54% identical to Y335_SYNY3: Uncharacterized protein sll0335 (sll0335) from Synechocystis sp. (strain PCC 6803 / Kazusa)

KEGG orthology group: None (inferred from 98% identity to ddc:Dd586_0369)

Predicted SEED Role

"Protein containing domains DUF404, DUF407"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CPQ0 at UniProt or InterPro

Protein Sequence (479 amino acids)

>DZA65_RS01940 circularly permuted type 2 ATP-grasp protein (Dickeya dianthicola ME23)
MIKMTLPAAPYYDEMLSAEGSQRQHYDAYWQWLQQTDQHAIRQKKEQAELLFHRVGITFN
VYGEEGGTERLIPFDSVPRIIPTHEWRMLDLGIRQRVKALNAFLYDIYHQQHILNVGIVP
REQVLANEQYQPCMQGVDLHNNIYAHITGIDMVRNSDGRYYVLEDNLRTPSGVSYMLENR
KMMMRLYPDLFASQHIAPVERYPSYLLQTLRESTHIDDPTVVVMTPGRFNSAYFEHSFLA
QQMGVELVESADLFVKEGAVYMRTTEGPCRVDVIYRRIDDAFLDPLAFRADSMLGVPGLL
SVYRAGGVVLANAIGTGVADDKSIYPYVPEMIRFYLSEEPILGNIPTWQCRKPDDLGYVL
AHLDSMVVKEVHGAGGYGMLVGPQSTRQQIEDFRQRLLANPGNYIAQDTLALSTCPTFVE
EGLAPRHIDLRPFVLYGEEIRLVPGGLTRVALTEGSLVVNSSQGGGTKDTWVMEEDESC