Protein Info for DZA65_RS00705 in Dickeya dianthicola ME23

Annotation: ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 632 PF00005: ABC_tran" amino acids 42 to 206 (165 residues), 98.4 bits, see alignment E=1.1e-31 amino acids 348 to 499 (152 residues), 107.9 bits, see alignment E=1.3e-34 PF08352: oligo_HPY" amino acids 257 to 289 (33 residues), 30 bits, see alignment (E = 1.1e-10) amino acids 551 to 589 (39 residues), 37.8 bits, see alignment 4.1e-13

Best Hits

Swiss-Prot: 60% identical to GSIA_ECOLI: Glutathione import ATP-binding protein GsiA (gsiA) from Escherichia coli (strain K12)

KEGG orthology group: K13892, glutathione transport system ATP-binding protein (inferred from 96% identity to dze:Dd1591_3970)

MetaCyc: 60% identical to glutathione ABC transporter ATP binding subunit GsiA (Escherichia coli K-12 substr. MG1655)
RXN0-11 [EC: 7.4.2.10]

Predicted SEED Role

"Dipeptide transport ATP-binding protein DppD (TC 3.A.1.5.2)" in subsystem ABC transporter dipeptide (TC 3.A.1.5.2) (TC 3.A.1.5.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A385XV99 at UniProt or InterPro

Protein Sequence (632 amino acids)

>DZA65_RS00705 ABC transporter ATP-binding protein (Dickeya dianthicola ME23)
MTDTPSTAIPAAIASDPAPQPVLEIDDLSVSFSGRSGTHLALKGVSFSLNKGEVVAVVGE
SGSGKSVTSLTVMGLLAASARIERGGIRFIDNAGRRHDLLTMKDDARRRLRGRDMAMIFQ
EPMTSLNPVLKVGDQLTEALLDHQMCDAASAERKARELLRKVRIADIDRVMNSYPHSLSG
GMRQRVMIAQALACDPQLLIADEPTTALDVTVQARILQILRDLQRQSNMSVLFITHDMGV
VAEIADRVVVMYRGEVVEQGTVDAIFNRPQHDYTKALLAAVPRLGDMRDSAWPKRFPLLG
QQNAAPEQDHTTARYDAPPLLDIRGLKVYYPIRSGILSSVTHRVHAVEQIDFTVWPGETL
AIVGESGCGKSTTGRALLRLVESQSDSLLFDGQEIAGLRDRDFQPLRRKMQMVFQDPYAS
LNPRLTVGFTIAEPLLLHGLAKSLEDATPQVQALLKSVGLLPEHAQRYPHEFSGGQRQRI
AIARAMALQPQVIIADEAVSALDVSIQAQVVNLMMDLQQKTGVSWIFISHDMAVVERIAN
RVAVMYLGQIVEIGPRQSVFNNPQHPYTRRLLASVPIADPNRRYARELDDSEIPSPLRKA
NEVVEKARYRNVAPHHWVSEAGLEPSVSSSKP