Protein Info for DZA65_RS00115 in Dickeya dianthicola ME23

Annotation: formyl-CoA transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 TIGR03253: formyl-CoA transferase" amino acids 8 to 424 (417 residues), 705.5 bits, see alignment E=9.4e-217 PF02515: CoA_transf_3" amino acids 9 to 402 (394 residues), 290.3 bits, see alignment E=1.2e-90

Best Hits

Swiss-Prot: 67% identical to FCTA_ECO81: Formyl-CoA:oxalate CoA-transferase (frc) from Escherichia coli O81 (strain ED1a)

KEGG orthology group: K07749, formyl-CoA transferase [EC: 2.8.3.16] (inferred from 98% identity to dda:Dd703_2501)

MetaCyc: 67% identical to formyl-CoA transferase (Escherichia coli K-12 substr. MG1655)
Formyl-CoA transferase. [EC: 2.8.3.16]

Predicted SEED Role

"Formyl-coenzyme A transferase (EC 2.8.3.16)" (EC 2.8.3.16)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 2.8.3.16

Use Curated BLAST to search for 2.8.3.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A3A4CJU4 at UniProt or InterPro

Protein Sequence (425 amino acids)

>DZA65_RS00115 formyl-CoA transferase (Dickeya dianthicola ME23)
MNNNKELPLAGVKIIDFTHVQAGPACTQMLAWFGADVVKIERPGSGDITRNQLRDIPDAD
ALYFTMLNSNKRSLTLDTKKPEGKEVLTRLIKESDVMVENFGPGALDRMGFTWEHIQELN
PRMILASVKGFSEGHHYEHLRAYENVAQCAGGAASTTGWWKGENAVPTISAAALGDSNTG
MHLAIGILTAYIGRQKTGKGQKVACAMQDAVLNLCRVKMRDQLRLDNVGYLEEYPQYPHE
PFSDVVPRGGNAGGGGQPGWILKCKGWESDPNAYIYFTVQDLVWTPICDAIERPEWREDP
AYTTPKARQPHIMDIFGAIESFILRTGKNKFDAVEYFGKFSIPCAPVMSMKELLHDESLR
KSGSIVEVPHKVRGSYWTVGCPIKFSTLKPEITASPLLGEHTDDVLAELGYSTEQIALIH
TAKAV