Protein Info for DDA3937_RS21315 in Dickeya dadantii 3937

Annotation: type II toxin-antitoxin system HipA family toxin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 439 PF13657: Couple_hipA" amino acids 4 to 103 (100 residues), 106.6 bits, see alignment E=8.4e-35 TIGR03071: HipA N-terminal domain" amino acids 4 to 104 (101 residues), 106.4 bits, see alignment E=3.6e-35 PF07804: HipA_C" amino acids 150 to 402 (253 residues), 183 bits, see alignment E=6.2e-58

Best Hits

KEGG orthology group: K07154, (no description) (inferred from 100% identity to ddd:Dda3937_01065)

Predicted SEED Role

"HipA protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SNG2 at UniProt or InterPro

Protein Sequence (439 amino acids)

>DDA3937_RS21315 type II toxin-antitoxin system HipA family toxin (Dickeya dadantii 3937)
MAALDVYMNGYRVGILTKTGSGAHHFSYDANWLGLPGNRPISLSMPLRHQPYQGDEVYNF
FDNLLPDNPDIRRRIVARHHADSTQPFDLLAKVGQDSVGALQLVPQGIPARDIKQIEYKT
LSEQQLESILSGYLSDAPLGMIDTEDDFRISIAGAQEKTALLYLDNHWCLPFNTTPTTHI
IKLPIGKIESHSYSIDMSDSVENEYLCLLIARAFGLPVPHCFMIKAGKIKALAVERFDRK
YASDGSWIMRLPQEDFCQVLNVPSALKYENHGGPGISAIMSYLLGAVDPQRDRYSFMKAQ
VLFWLLAATDGHAKNFSLFIESEGRYRLTPFYDILSMYPAFGGRGIDRRDAKLAMGLAGT
RGKKYHIEQIFPRHFFQTAKAVGFARESMERILTEFSQTVDSVIVSVRNQLPADFPTPIR
DAILGGLQTRSRRLTTGWE