Protein Info for DDA3937_RS13860 in Dickeya dadantii 3937

Annotation: type IV secretion system protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 227 transmembrane" amino acids 30 to 53 (24 residues), see Phobius details PF04335: VirB8" amino acids 12 to 223 (212 residues), 169 bits, see alignment E=7.2e-54

Best Hits

KEGG orthology group: K03203, type IV secretion system protein VirB8 (inferred from 100% identity to ddd:Dda3937_02748)

Predicted SEED Role

"Inner membrane protein forms channel for type IV secretion of T-DNA complex (VirB8)" in subsystem Type 4 secretion and conjugative transfer or pVir Plasmid of Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E0SJI6 at UniProt or InterPro

Protein Sequence (227 amino acids)

>DDA3937_RS13860 type IV secretion system protein (Dickeya dadantii 3937)
MSETENLIASSRTFEAVLLEKDEREKKRAWRMAATGFALAALTITALIILLPLKTTDIEL
WSVDKQTGRYEYMTRLKEKDIATEAALAHALSAQYVRLREGYNYFALQRDYDDVQLFNSD
SVNRDYLDEFNGNQAPDVIFNKAEYVVSVEIISNIHAPATAPDHLATLRVKRIIRRIADN
TVKTDIWNIRLTYRYLPHKQLTDSQREVNPLGFIVTSYQRDKELRGE