Protein Info for CCNA_00674 in Caulobacter crescentus NA1000 Δfur

Annotation: NAD(FAD)-utilizing dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 415 PF12831: FAD_oxidored" amino acids 20 to 54 (35 residues), 27.8 bits, see alignment 5.9e-10 PF01494: FAD_binding_3" amino acids 20 to 53 (34 residues), 24.3 bits, see alignment 6.1e-09 PF00890: FAD_binding_2" amino acids 20 to 69 (50 residues), 34.4 bits, see alignment 5.2e-12 PF03486: HI0933_like" amino acids 20 to 408 (389 residues), 248.1 bits, see alignment E=3.1e-77 TIGR00275: flavoprotein, HI0933 family" amino acids 21 to 408 (388 residues), 276.4 bits, see alignment E=3.7e-86 PF13450: NAD_binding_8" amino acids 23 to 54 (32 residues), 27 bits, see alignment (E = 1.5e-09) TIGR03862: flavoprotein, TIGR03862 family" amino acids 43 to 411 (369 residues), 486.3 bits, see alignment E=5.6e-150 PF22780: HI0933_like_1st" amino acids 207 to 357 (151 residues), 103 bits, see alignment E=5.6e-33

Best Hits

KEGG orthology group: K07007, (no description) (inferred from 100% identity to ccs:CCNA_00674)

Predicted SEED Role

"NAD(FAD)-utilizing dehydrogenases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0H3C4C5 at UniProt or InterPro

Protein Sequence (415 amino acids)

>CCNA_00674 NAD(FAD)-utilizing dehydrogenase (Caulobacter crescentus NA1000 Δfur)
MTFPKPTSWPPDVTDERILDVAVIGGGPAGLMAAETVAKAGRSVAVFEKMPTFGRKFLMA
GRGGLNLTHSEDFDRFATRYGERSATLRPMLEAFTPQDLVTWAEGLGQTTFVGASGRVFP
KAMKASPLLRAWLSRLEDLGVSLRPRSTWRGWDAMGGLRIDDPNGRNTVRARVTILALGG
ASWPKLGSDAAWAPLLRVGGSEIAPFRPANCGFDVAWSTMFRDRFAGEPLKNIALRLGEA
RARGDAVIARYGLEGGAIYALGGAARDAALAGGATLTVDLRPDIPVETLERRLHAPRGGQ
SLANFLRKAVKLSPVEVNLLREAHGLDLPVEPAALAAAIKAAPIRLTGVQPLDRAISSAG
GVRFESLDGLTLKGRPDVLLAGEMLDWEAPTGGYLLQACFATGVAAGRAALERLG