Protein Info for CA264_17975 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: S9 family peptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 744 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF00930: DPPIV_N" amino acids 108 to 450 (343 residues), 366.2 bits, see alignment E=7.7e-113 PF07676: PD40" amino acids 214 to 224 (11 residues), 13.6 bits, see alignment (E = 3e-05) PF02129: Peptidase_S15" amino acids 493 to 645 (153 residues), 42.9 bits, see alignment E=2.8e-14 PF00756: Esterase" amino acids 495 to 717 (223 residues), 27.1 bits, see alignment E=1.8e-09 PF00326: Peptidase_S9" amino acids 541 to 735 (195 residues), 192.8 bits, see alignment E=3e-60 PF01738: DLH" amino acids 577 to 713 (137 residues), 24.6 bits, see alignment E=9.8e-09

Best Hits

KEGG orthology group: K01278, dipeptidyl-peptidase 4 [EC: 3.4.14.5] (inferred from 54% identity to shg:Sph21_2473)

Predicted SEED Role

"Dipeptidyl peptidase IV"

Isozymes

Compare fitness of predicted isozymes for: 3.4.14.5

Use Curated BLAST to search for 3.4.14.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YW90 at UniProt or InterPro

Protein Sequence (744 amino acids)

>CA264_17975 S9 family peptidase (Pontibacter actiniarum KMM 6156, DSM 19842)
MHIRLKTNLLAAVLLCFAFVAQAQQKKDITLEDLYKKGTFRSQSVYGVNWMNDGRYYSSM
VPDEQHKVYDIVKYDVTTGKPVSTIIEGENLVPAGSNQPIQYDDYTFSSDEQKVLFSTDT
EQIYRRSSKANFYIYDIASKKLTKLSDGGKQMYASFSPDAKRVAFARENNMFVTDLSNMQ
ETQITTDGKFNSIINGYSDWVYEEEFSFAKGFHWSPDGKKIAFYTFDEANVPEFNMQMWG
ELYPQDYKFKYPKAGEANSTVKVSVYDVNSGKTVKMDTGNEDDIYIPRIKWTNDPNLLSI
QKMNRLQNTLEILHANASTGKTNVVLKETDKAYIDITDDLTYLEDGKNFIHSSEKDGYNH
LYLYNMNGKLVRQITDGNWEVSEYVGYDEKNDRLYYMSTEVSPLDRHLYSISSKGKKKQR
LTEKSGTHNINMSNDFKYYLDYYSAANTPPTVSLHTAKDGKLIKVLEDNEKLKNTLAQYD
IAKQEFFTMNTADGTKLNGWMIKPTDFDPNKKYPVLMFVYGGPGSQTVTNSWGGSNYLWH
QVLADKGLIVVSVDNRGTGARGADFKKITYANLGKYEIEDQIEAAKWLGKQSYVDKDRIG
IWGHSFGGYMTLLGLTKGDGVFRAGISVAPVTNWRFYDSIYTERYLKTPQENAAGYDENS
PLFFADKLQGKLLLIHGTGDDNVHFQNAVAMQDALIDANKQFESFYYPNRNHGIYGGNTY
MHRFTMMTDFLERNLINPTTEKNQ