Protein Info for CA264_17535 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: peptidylprolyl isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 701 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details PF13623: SurA_N_2" amino acids 4 to 150 (147 residues), 135.9 bits, see alignment E=2.5e-43 PF13624: SurA_N_3" amino acids 4 to 172 (169 residues), 60.3 bits, see alignment E=5.3e-20 PF13145: Rotamase_2" amino acids 223 to 340 (118 residues), 36.4 bits, see alignment E=2.1e-12 PF13616: Rotamase_3" amino acids 329 to 444 (116 residues), 115.2 bits, see alignment E=6.2e-37 PF00639: Rotamase" amino acids 348 to 441 (94 residues), 86.4 bits, see alignment E=5.6e-28

Best Hits

KEGG orthology group: K03770, peptidyl-prolyl cis-trans isomerase D [EC: 5.2.1.8] (inferred from 46% identity to sli:Slin_6025)

Predicted SEED Role

"Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8)" in subsystem Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)

Isozymes

Compare fitness of predicted isozymes for: 5.2.1.8

Use Curated BLAST to search for 5.2.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YW49 at UniProt or InterPro

Protein Sequence (701 amino acids)

>CA264_17535 peptidylprolyl isomerase (Pontibacter actiniarum KMM 6156, DSM 19842)
MALINKIREKSGWAVGVIALGLGVFIVGGDLLGPNSRLLGNDANVVGEIAGEEIDYQEFD
AVLQQVKADYENRIGRAANEGELAMLREQAWNQLIFKIALQKEYDRLGLEVTDEELADMV
QGNNIHPAVMQAFTNPQTGEFDRSQVVQYLQNLDQTGTRPMWVNFEQSIAADRLQGKYAN
LLSKTVYITDAEAKNYYKAQNAAASMKVLYVPFFTISDSAVEVTDAQLKDYYERNKELYK
VEDGRTIEFVTIPVAASKEDSTYYNEEIATITQQFASAPNDSAFVNANSDVAYDGTYRTP
GELPEELRKQLPLQEGKVYGPYNNNGSVALFKVIDAKEADKSAARASHILIRPENDTPEA
KAAAKEKAQDVLNQIKGGADFAQMAAQYGTDGTASRGGDLGWFPEGQMVPAFEKAIFNSN
GTGLLPNLVETEYGYHIVKVTEPKTNNTYKVASVVRTIEPSETTRDAAYAIADELAGTSS
STEEFRENVAQNKSLVKEESANIGKNQVLVNNLANARELVRWTYAKDSEVGDVSPVYEIN
DQFVVATLTGKREKGYADIKDVKDELTAAVRSELKAKQIMEKLNGQKGSLDQIAAAYGPD
AMVKSADNVTFASAAIPGLGVEPVAVGKAFGLKQGGRTAPFEGQGGVMIVELTNMTPAPE
INDFSNVKEQMRMTRSGRAESNAFEAIKEKSDITDNRVRFF