Protein Info for CA264_08730 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: efflux transporter periplasmic adaptor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 360 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 39 to 342 (304 residues), 228 bits, see alignment E=7.2e-72 PF16576: HlyD_D23" amino acids 60 to 260 (201 residues), 74.3 bits, see alignment E=1.7e-24 PF13533: Biotin_lipoyl_2" amino acids 65 to 104 (40 residues), 41.7 bits, see alignment 1.6e-14 PF13437: HlyD_3" amino acids 154 to 258 (105 residues), 52.2 bits, see alignment E=1.8e-17

Best Hits

KEGG orthology group: K03585, membrane fusion protein (inferred from 75% identity to shg:Sph21_1486)

Predicted SEED Role

"Probable Co/Zn/Cd efflux system membrane fusion protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YRL5 at UniProt or InterPro

Protein Sequence (360 amino acids)

>CA264_08730 efflux transporter periplasmic adaptor subunit (Pontibacter actiniarum KMM 6156, DSM 19842)
MKRILMLMGLCALLCNTSCESKKEEKEEKVTFMVTSPMKMDTTVTKDYVSQIHSISHIEL
RAQERGYLQKIFVDEGQTVKKGQLLFQITPTLYEAELQSAQAEVNFADIEYQNTKKLADS
NIVSPNELAMAKAKLDKAKAELALAKVHLQFTQIKAPFDGIIDRFHVRLGSLVDEGELLT
NLSDNSKMWVYYNVPEAEYLDYKSHEKQDSAVKVKLLMANNKLFSHPGVVETIEADFNNE
TGNIPFRATFPNPDRLLRHGETGNILMSVPLSNALLIPQKATFEVLDKKYVYVVDKDGVL
KSREITVAAEMPHIYAVQDGLAEGDKFLLEGLRLVRENEKIHYKFVEPSTVLSQLDLYAE