Protein Info for CA264_07535 in Pontibacter actiniarum KMM 6156, DSM 19842

Annotation: sigma-54-dependent Fis family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 461 PF00072: Response_reg" amino acids 9 to 123 (115 residues), 64.9 bits, see alignment E=3.4e-21 PF00158: Sigma54_activat" amino acids 157 to 323 (167 residues), 227.4 bits, see alignment E=4e-71 PF14532: Sigma54_activ_2" amino acids 159 to 328 (170 residues), 82.6 bits, see alignment E=1.5e-26 PF07724: AAA_2" amino acids 179 to 307 (129 residues), 28.1 bits, see alignment E=8.9e-10 PF07728: AAA_5" amino acids 180 to 300 (121 residues), 39.2 bits, see alignment E=3.2e-13 PF00004: AAA" amino acids 181 to 300 (120 residues), 26.4 bits, see alignment E=3.7e-09 PF02954: HTH_8" amino acids 419 to 459 (41 residues), 53.2 bits, see alignment 9.1e-18

Best Hits

KEGG orthology group: None (inferred from 57% identity to mtt:Ftrac_3412)

Predicted SEED Role

"Two-component system response regulator" in subsystem Streptococcal Mga Regulon or Two-component regulatory systems in Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1X9YR10 at UniProt or InterPro

Protein Sequence (461 amino acids)

>CA264_07535 sigma-54-dependent Fis family transcriptional regulator (Pontibacter actiniarum KMM 6156, DSM 19842)
MEEQNLGRILVIDDNEDVLFSAKMLLRKHAREVVMEKNPKKIPFLLSNEDFDLILLDMNF
SQDITSGQEGFYWLKEVLKYDPSAVVVMITAYGDVEMAVKALKEGATDFVLKPWQNEKLL
ATLSAAARLRHSYQEVSRLREANRTLSTQLHSGKDIIQGESKAMRHLFSIIDKVAKTDAD
ILLLGENGTGKEVIARALHERSSRADKVFVTVDMGAITESLFESELFGHKKGAFTDAKED
RVGRIEAANGGTLFLDEIGNLSPAMQAKLLTVLQRREIIKVGTNKPVPVNVRLICATNMP
LKEMVQRGEFRQDLLYRINTVELQLPPLRSRQDDLPLFAAHFLQVYAVKYKQPVKRLSDA
ALARLKSYSWPGNVRELQHALERASIMSDNRELQPDDFFFLAEEEAVEASAVSAQSLDLD
ELEREAVQRALQKHEGNISKAAKELGLSRGALYRRLEKYEL