Protein Info for BNILDI_17550 in Escherichia coli ECRC62

Name: yddG
Annotation: aromatic amino acid efflux DMT transporter YddG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 274 transmembrane" amino acids 13 to 34 (22 residues), see Phobius details amino acids 45 to 67 (23 residues), see Phobius details amino acids 74 to 94 (21 residues), see Phobius details amino acids 101 to 119 (19 residues), see Phobius details amino acids 139 to 156 (18 residues), see Phobius details amino acids 163 to 184 (22 residues), see Phobius details amino acids 196 to 214 (19 residues), see Phobius details amino acids 224 to 246 (23 residues), see Phobius details amino acids 252 to 271 (20 residues), see Phobius details PF00892: EamA" amino acids 139 to 266 (128 residues), 35.3 bits, see alignment E=6.6e-13

Best Hits

Swiss-Prot: 99% identical to YDDG_ECOLI: Aromatic amino acid exporter YddG (yddG) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to eco:b1473)

MetaCyc: 99% identical to amino acid exporter YddG (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-265

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (274 amino acids)

>BNILDI_17550 aromatic amino acid efflux DMT transporter YddG (Escherichia coli ECRC62)
MVGLIRGVSEGLGPVGGAAAIYSLSGLLLIFTVGFPRIRQIPKGYLLAGSLLFVSYEICL
ALSLGYAATRHQAIEVGMVNYLWPSLTILFAILFNGQKTNWLIVPGLLLALVGVCWVLGG
DNGLHYDEIINNITTSPLSYFLAFIGAFIWAAYCTVTNKYARGFNGITVFVLLTGASLWV
YYFLTPQPEMVFSTPVMIKLISAAFTLGFAYAAWNVGILHGNVTIMAVGSYFTPVLSSAL
AAVLLSAPLSFSFWQGALMVCGGSLLCWLATRRG