Protein Info for BACOVA_05458 in Bacteroides ovatus ATCC 8483

Annotation: sigma factor regulatory protein, FecR/PupR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 284 transmembrane" amino acids 42 to 63 (22 residues), see Phobius details PF04773: FecR" amino acids 86 to 170 (85 residues), 55.8 bits, see alignment E=2.7e-19

Best Hits

KEGG orthology group: None (inferred from 65% identity to bth:BT_4644)

Predicted SEED Role

"Possible anti-sigma factor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (284 amino acids)

>BACOVA_05458 sigma factor regulatory protein, FecR/PupR family (Bacteroides ovatus ATCC 8483)
MKTDIYKIKTDQAWNRLYNRLDNDRLLAKVDEGHHTRKYSQWIRYGAVAAVLIGVIWGTL
YWVTGSDKELAQHLLTQENQGVSTLATTLEDGSVVLLAKETSLLYPKHFIADKREVSLQG
NAFFDVAKKQGQPFWIDTEQAKIEVLGTAFSVQSDENAPFRLSVQRGIVKVTLKKGNQEC
YVKAGETVVVRSQRLVVLDTDKENEEWGSFFKHIRFKDESLANILKVMNLNSDSLQIQVV
SPALEERRLTVEFSDESSEVIANLIASALGLQCIRQGDILLLSE