Protein Info for BACOVA_05182 in Bacteroides ovatus ATCC 8483

Annotation: glycosyl hydrolase family 35

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 777 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF01301: Glyco_hydro_35" amino acids 39 to 349 (311 residues), 379.5 bits, see alignment E=4.3e-117 PF02449: Glyco_hydro_42" amino acids 58 to 196 (139 residues), 35.6 bits, see alignment E=1.8e-12 PF21317: BetaGal_ABD_1" amino acids 394 to 504 (111 residues), 92.6 bits, see alignment E=4.1e-30 PF21467: BetaGal_gal-bd" amino acids 523 to 581 (59 residues), 91.2 bits, see alignment 8.7e-30 PF00754: F5_F8_type_C" amino acids 698 to 769 (72 residues), 30.6 bits, see alignment E=8.1e-11

Best Hits

Predicted SEED Role

"Beta-galactosidase (EC 3.2.1.23)" in subsystem Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Lactose utilization (EC 3.2.1.23)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.23

Use Curated BLAST to search for 3.2.1.23

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (777 amino acids)

>BACOVA_05182 glycosyl hydrolase family 35 (Bacteroides ovatus ATCC 8483)
MKMNKNHKTVLVILNIIVSFLISSCSSPKEQVRIGNGTFTIEGKDIQLICGEMHYPRIPH
EYWRDRLKRASAMGLNTVSAYVFWNFHERQPGEFDFSGQADIAEFIRTAQEEGLYVILRP
GPYVCAEWDFGGYPSWLLKEKDMTYRSKDPRFLSYCERYIKELGKQLSPLTINNGGNIIM
VQVENEYGSYAADKEYLAAIRDMIKEAGFNVPLFTCDGGGQVEAGHVEGALPTLNGVFGE
DIFKVVDKYQKGGPYFVAEFYPAWFDEWGRRHSSVAYERPAEQLDWMLSHGVSVSMYMFH
GGTNFEYTNGANTGGGYQPQPTSYDYDAPLGEWGNCYPKYHAFREVIQKYLPAGTVLPEV
PADNPTTTFATVELKESAPLRTAFHQTTQSENVLSMEDLGVDFGYIHYQTTLQKAGKQKL
VIQDLRDYAVILIDGKQVASLDRRYNQNSVTLNVSKTPATLEILVENTGRVNYGPDILFN
RKGITSQVLWGNEKLAGWSITPLPLYKEKVSEMEFGETIKGVPAFHKGTFTVEKKGDCFV
DMSQWGKGAVWVNGKSLGRFWNIGPQQTLYLPAPWLKEGENEIVVFEMEDTGKRVLQGLN
QPILDSLGIDKNYQKGQRRAVVGTPILEDGDLALKTTLQETNEWQSFDLPVATTLRHFCI
ETLSSYTEDNQACISEVELIDDKGQPIDKTKWEVVYVSSEQADKNLGIAENLFDGDISSF
WHTNAAVESNHPHRVIIDLKEIYKVSAFRVKVRKGSFLSGKVKDINIYGRPQFFLFH