Protein Info for BACOVA_05141 in Bacteroides ovatus ATCC 8483

Annotation: glycosyl hydrolase family 20, catalytic domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 809 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF02838: Glyco_hydro_20b" amino acids 29 to 160 (132 residues), 88.8 bits, see alignment E=9.9e-29 PF00728: Glyco_hydro_20" amino acids 164 to 525 (362 residues), 429.2 bits, see alignment E=3e-132 PF13290: CHB_HEX_C_1" amino acids 571 to 626 (56 residues), 43.4 bits, see alignment 5.3e-15 PF13287: Fn3_assoc" amino acids 573 to 630 (58 residues), 67.2 bits, see alignment 2.2e-22

Best Hits

KEGG orthology group: K12373, hexosaminidase [EC: 3.2.1.52] (inferred from 90% identity to bth:BT_4337)

Predicted SEED Role

"Beta-hexosaminidase (EC 3.2.1.52)" in subsystem Chitin and N-acetylglucosamine utilization or N-Acetyl-Galactosamine and Galactosamine Utilization (EC 3.2.1.52)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.52

Use Curated BLAST to search for 3.2.1.52

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (809 amino acids)

>BACOVA_05141 glycosyl hydrolase family 20, catalytic domain protein (Bacteroides ovatus ATCC 8483)
MKKSISLLLLSLLMITPSCQKTKEAANEYNIVPKPNQILPQEGRFELNNKVCLVVLSDAP
EVKSIADSLAEQLKLTAGISLKEAESADGKTAISFVVQEGMPKEGYKLSVTPSLITLTAS
QPNGFFYGVQTLYQLLPPAIYGKQLDKKADWSVPAVEIEDSPRFVHRGLMLDVCRHYVPI
DYIYKFIDLLAMNKMNVFHWHLTDDQGWRIEIKKYPKLTEIGSKREKTLVDYYYVNYPQV
FDGKEHGGYYTQEQIKDVVAYAASKYINVVPEIEMPGHALAALAAYPELSCDSTQTYKVS
PTWGVFEQVFCPSETTFKFFEGVMDEVIELFPSEYIHIGGDECPKTAWKNSAFCQQLIRQ
LGLKDDTTPSKIDGIKHSKEDKLQSYFVTRMEKYLNSKGKNIIGWDEILEGGLAPNATVM
SWRGVEGGMNAAKAGHNAIMTPNPYVYLDYYQEEPEIAPTTIGGYNTLKKTYSYNPVPDD
ADELAKKHIIGIQGNIWREYMQTSERTDYQAFPRAMAIAETAWTQNANKDWKNFCERMVT
EFERLKVMNTQPCLNFYDVNINTHADENGPLMVLLESFYPNAEIRYTTDGSEPSKVSILY
EKPFVLEGNIDLKAAAFKDGKMLGKVAHKPLYGNLLTGKPYTVNYTMGWTGDIFDENDVL
GADKTTFGLTNGKRGNNASYTPWCSFGIVEGKDLEFIVHLDKPTQVSKVIFGSLFNPAMR
ILPAGGVAVEVSADGKQYTRIAEKALKHDYPETGRIAFTDSIEFEPAQATFLKVKIKNGG
TLRNGVNFEKNNGPEVIPAELWIDEIEAY