Protein Info for BACOVA_03280 in Bacteroides ovatus ATCC 8483

Annotation: TrkA C-terminal domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 554 transmembrane" amino acids 13 to 31 (19 residues), see Phobius details amino acids 38 to 58 (21 residues), see Phobius details amino acids 69 to 89 (21 residues), see Phobius details amino acids 99 to 121 (23 residues), see Phobius details amino acids 162 to 187 (26 residues), see Phobius details amino acids 376 to 396 (21 residues), see Phobius details amino acids 402 to 422 (21 residues), see Phobius details amino acids 442 to 463 (22 residues), see Phobius details amino acids 469 to 493 (25 residues), see Phobius details amino acids 501 to 509 (9 residues), see Phobius details amino acids 533 to 552 (20 residues), see Phobius details PF06826: Asp-Al_Ex" amino acids 21 to 183 (163 residues), 146.6 bits, see alignment E=6.4e-47 amino acids 379 to 550 (172 residues), 158.8 bits, see alignment E=1.1e-50 TIGR01625: AspT/YidE/YbjL antiporter duplication domain" amino acids 27 to 171 (145 residues), 117.4 bits, see alignment E=2.4e-38 amino acids 384 to 537 (154 residues), 149.1 bits, see alignment E=4.4e-48 PF02080: TrkA_C" amino acids 212 to 275 (64 residues), 32.6 bits, see alignment E=6e-12 amino acids 303 to 363 (61 residues), 48.4 bits, see alignment E=7.1e-17

Best Hits

Swiss-Prot: 97% identical to Y2092_BACTN: Uncharacterized transporter BT_2092 (BT_2092) from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

KEGG orthology group: K07085, putative transport protein (inferred from 97% identity to bth:BT_2092)

Predicted SEED Role

"putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (554 amino acids)

>BACOVA_03280 TrkA C-terminal domain protein (Bacteroides ovatus ATCC 8483)
MDWLQSLLWDPSSVAHIVLLYAFVVAAGVYLGKIKIFGVSLGVTFVLFAGILMGHFGFTA
DTHILHFIREFGLILFVFCIGLQVGPSFFSSFKKGGMTLNLLAVGIVVLNIAVALGLYYL
WNDRVELPMMVGILYGAVTNTPGLGAANEALNQLHYTGPQIALGYACAYPLGVVGIIGSI
IAIRYIFRVNMAKEEESLKIQSGDSHHKPHMMSLEVRNESISGKTLIEIKNFLGRKFVCS
RIRHDGHVSIPDHETVFNIGDQLFIVCSEEDAPAIVVFIGKEVELDWEKQDLPMVSRRIL
VTKPEINGKTLGSMHFRSMYGVNVTRINRSGMDLFADPNLILQVGDRVMVVGQQDAVERV
AGVLGNQLKRLDTPNIVTIFVGIFLGILLGSLPIAFPGMPTPLKLGLAGGPLVVAILIGR
FGHKLHLVTYTTMSANLMLREIGIVLFLASVGIDAGANFVQTVVEGDGLLYVGSGFLITV
IPLLIIGTIARLYYKVNYFTLMGLIAGSNTDPPALAYANQTTSGDAPAVGYSTVYPLSMF
LRILTGQMILLAMM