Protein Info for BACOVA_02645 in Bacteroides ovatus ATCC 8483
Annotation: glycosyl hydrolase family 2, sugar binding domain protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to BGH2A_BACO1: Beta-galactosidase BoGH2A (BACOVA_02645) from Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / NCTC 11153)
KEGG orthology group: None (inferred from 76% identity to bsa:Bacsa_0882)Predicted SEED Role
"Beta-galactosidase (EC 3.2.1.23)" in subsystem Galactosylceramide and Sulfatide metabolism or Lactose and Galactose Uptake and Utilization or Lactose utilization (EC 3.2.1.23)
MetaCyc Pathways
- lactose degradation III (1/1 steps found)
- xyloglucan degradation II (exoglucanase) (5/8 steps found)
KEGG Metabolic Maps
- Galactose metabolism
- Glycosaminoglycan degradation
- Glycosphingolipid biosynthesis - ganglio series
- Other glycan degradation
- Sphingolipid metabolism
Isozymes
Compare fitness of predicted isozymes for: 3.2.1.23
Use Curated BLAST to search for 3.2.1.23
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (851 amino acids)
>BACOVA_02645 glycosyl hydrolase family 2, sugar binding domain protein (Bacteroides ovatus ATCC 8483) MMIGKLKYLMLGGCLILGSCLALGGCLMLLGACSSSSLVSPRERSDFNADWRFHLGDGLQ AAQPGFADNDWRVLDLPHDWAIEGDFSQENPSGTGGGALPGGVGWYRKTFSVDKADAGKI FRIEFDGVYMNSEVFINGVSLGVRPYGYISFSYDLTPYLKWDEPNVLAVRVDNAEQPNSR WYSGCGIYRNVWLSKTGPIHVGGWGTYVTTSSVDEKQAVLNLATTLVNESDTNENVTVCS SLQDAEGREVAETRSSGEAEAGKEVVFTQQLTVKQPQLWDIDTPYLYTLVTKVMRNEECM DRYTTPVGIRTFSLDARKGFTLNGRQTKINGVCMHHDLGCLGAAVNTRAIERHLQILKEM GCNGIRCSHNPPAPELLDLCDRMGFIVMDEAFDMWRKKKTAHDYARYFNEWHERDLNDFI LRDRNHPSVFMWSIGNEVLEQWSDAKADTLSLEEANLILNFGHSSEMLAKEGEESVNSLL TKKLVSFVKGLDPTRPVTAGCNEPNSGNHLFRSGVLDVIGYNYHNKDIPNVPANFPDKPF IITESNSALMTRGYYRMPSDRMFIWPKRWDKSFADSTFACSSYENCHVPWGNTHEESLKL VRDNDFISGQYVWTGFDYIGEPTPYGWPARSSYFGIVDLAGFPKDVYYLYQSEWTDKQVL HLFPHWNWTPGQEIDMWCYYNQADEVELFVNGKSQGVKRKDLDNLHVAWRVKFEPGTVKV IARESGKVVAEKEICTAGKPAEIRLTPDRSILTADGKDLCFVTVEVLDEKGNLCPDADNL VNFTVQGNGFIAGVDNGNPVSMERFKDEKRKAFYGKCLVVIQNDGKPGKAKLTATSEGLR QAVLKISAEEL