Protein Info for BACOVA_02442 in Bacteroides ovatus ATCC 8483

Annotation: aspartate-alanine antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 564 transmembrane" amino acids 12 to 28 (17 residues), see Phobius details amino acids 34 to 54 (21 residues), see Phobius details amino acids 60 to 77 (18 residues), see Phobius details amino acids 89 to 110 (22 residues), see Phobius details amino acids 157 to 180 (24 residues), see Phobius details amino acids 390 to 409 (20 residues), see Phobius details amino acids 415 to 433 (19 residues), see Phobius details amino acids 454 to 473 (20 residues), see Phobius details amino acids 479 to 501 (23 residues), see Phobius details amino acids 511 to 529 (19 residues), see Phobius details amino acids 541 to 563 (23 residues), see Phobius details TIGR03802: aspartate-alanine antiporter" amino acids 2 to 564 (563 residues), 713.2 bits, see alignment E=2.4e-218 PF06826: Asp-Al_Ex" amino acids 15 to 175 (161 residues), 142 bits, see alignment E=1.6e-45 amino acids 393 to 561 (169 residues), 158.2 bits, see alignment E=1.8e-50 TIGR01625: AspT/YidE/YbjL antiporter duplication domain" amino acids 22 to 167 (146 residues), 74.8 bits, see alignment E=6.7e-25 amino acids 398 to 547 (150 residues), 95.9 bits, see alignment E=2.1e-31

Best Hits

Swiss-Prot: 91% identical to Y736_BACTN: Uncharacterized transporter BT_0736 (BT_0736) from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

KEGG orthology group: K07085, putative transport protein (inferred from 91% identity to bth:BT_0736)

Predicted SEED Role

"putative transport protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (564 amino acids)

>BACOVA_02442 aspartate-alanine antiporter (Bacteroides ovatus ATCC 8483)
MEWIINQLRVHPELAIFLTLFAGFWLGRLKIGKFSLGTVTSVLLVGVLVGQLNITVDGPM
KAVFFLLFLFAVGYKVGPQFFRGLKKDGLPQVGFAVLMCIVSLVAPWILAKIMGYHVGEA
AGLLAGSQTISAVIGVASDTINQLGISDAQKATFINAIPVAYAVTYIFGTAGSAWILASL
GPKMLGGLDKVKADCKELEAQMGTSEADEPGFSPALRPVVFRAYKITNEWFDKGKKVSEL
EAYLCKNDKRLFVERIRQKRVVKEVDPNLILHKNDEVVLSGRREFVIGEEDWIGPEVIDA
QLLDFPAETLPVMVTHRTFAGETVSKIRAQKFMHGVSIRNIKRAGINVPVLPKTIVDSGD
ILELTGLKHEVESAAKQMGYIDRPTNQTDMIFVGLGILLGGLFGALAIHLGGVPISLSTS
GGALIAGLLFGWLRSKHPTFGGIPEPSLWVLNNVGLNMFIAVVGIAAGPSFIAGFKEVGV
SLFIVGALATAIPLLAGLLMARYLFKFHPALSLGCTAGARTTTAALGAIQDAVESDTPAL
GYTVTYAVGNTLLIIWGVVIVLLM