Protein Info for BACOVA_00675 in Bacteroides ovatus ATCC 8483
Annotation: heavy metal efflux pump, CzcA family
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 96% identity to bth:BT_2039)Predicted SEED Role
"Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (1032 amino acids)
>BACOVA_00675 heavy metal efflux pump, CzcA family (Bacteroides ovatus ATCC 8483) MLNKIIHYSLHNRLVVVCAAILLLIAGTYTAMHTEVDVFPDLNAPTVVIMTEANGMAAEE VEQLVTFPVETAVNGATGVRRVRSSSTNGFSVVWVEFDWGTDIYLARQIVSEKLAVVSES LPVNVGKPTLGPQSSILGEMLIIGLTADSTSMLDLRTIADWTIRPRLLSTGGVAQVAVLG GDIKEYQIQLDPERMRHYGISMGEVMAVTQDMNLNANGGVLYEFGNEYIVRGVLSTSKTE QLGKAVVKTVNNFPVTLEDIANVTIGPKAPKLGTASERGKSAVLMTVTKQPATSTLELTD KLEASLKDLQKNLPPDVKVSTDIFRQSRFIESSIGNVKKSLFEGGIFVVIVLFLFLANVR TTLISLVTLPLSLLVSILTLHYMGLTINTMSLGGMAIAIGSLVDDAIVDVENVYKRLREN RLKVEAERLSTLEVVFNASKEVRMPILNSTLIIVVSFVPLFFLSGMEGRMLVPLGVAFIV ALFASTIVALTLTPVLCSYLLGSNKTNKELKEAPVARWMKGIYEKALTWVLAHKRVTLGS TIGLFVVALGVFFTLGRSFLPSFNEGSFTINISSLPGISLEESNKMGHRAEELLMTIPEI QTVARKTGRAELDEHALGVNVSEIEAPFELKDRSRSELVADVREKLGTITGANIEIGQPI SHRIDAMLSGTKANIAIKLFGDDLNKMFSLGNQIKGAISDIPGVADLNVEQQIERPQLKI QPKREMLAKFGITLPEFSEYVNVALAGKVISQVYEQGKSFDLIVKVKDDARDEIEKIRNL MVDTNDGRKVPLSYVAEVVSAMGPNTINRENVKRKIVISANVADRDLRSVVNDIQKRIDT SVQLPEGYHIEYGGQFESEQAASRTLALTSFISIVVIFLLLYNEFRSVKESGVILLNLPL ALIGGVFALVITTGEVSIPAIIGFISLFGIATRNGMLLISHYNHLQKEEGLNVYDSVIQG SLDRLNPILMTALSSALALIPLALAGDLPGNEIQSPMAKVILGGLLTSTFLNGFIVPIVY LMMHRKKAQKSL