Protein Info for BACOVA_00381 in Bacteroides ovatus ATCC 8483

Annotation: putative thioredoxin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 75 99 PF00085: Thioredoxin" amino acids 2 to 95 (94 residues), 91.8 bits, see alignment E=3.7e-30 TIGR01068: thioredoxin" amino acids 2 to 97 (96 residues), 104.3 bits, see alignment E=1.7e-34 PF13098: Thioredoxin_2" amino acids 13 to 92 (80 residues), 37 bits, see alignment E=5.7e-13

Best Hits

Swiss-Prot: 45% identical to THIO2_CORNE: Thioredoxin C-2 from Corynebacterium nephridii

KEGG orthology group: None (inferred from 90% identity to bth:BT_0219)

MetaCyc: 38% identical to reduced thioredoxin 1 (Escherichia coli K-12 substr. MG1655)
RXN-20161 [EC: 1.8.4.16]

Predicted SEED Role

"TRX family"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.8.4.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (99 amino acids)

>BACOVA_00381 putative thioredoxin (Bacteroides ovatus ATCC 8483)
MEKFEDLIQSPVPVLVDFFAGWCGPCKAMKPVLEELKLIVGDKARIAKIDVDQHEDLATK
YRIQAVPTFILFKNGEAVWRHSGIIHSSELQGVIEKHYT