Protein Info for B158DRAFT_2312 in Kangiella aquimarina DSM 16071

Annotation: polyphosphate kinase 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 711 TIGR03705: polyphosphate kinase 1" amino acids 37 to 701 (665 residues), 924 bits, see alignment E=2.8e-282 PF13089: PP_kinase_N" amino acids 38 to 143 (106 residues), 127.7 bits, see alignment E=5.7e-41 PF02503: PP_kinase" amino acids 152 to 336 (185 residues), 194.2 bits, see alignment E=4.3e-61 PF17941: PP_kinase_C_1" amino acids 363 to 526 (164 residues), 246.6 bits, see alignment E=2.5e-77 PF13091: PLDc_2" amino acids 409 to 522 (114 residues), 29.6 bits, see alignment E=1.3e-10 PF13090: PP_kinase_C" amino acids 535 to 701 (167 residues), 208.7 bits, see alignment E=1.1e-65

Best Hits

Swiss-Prot: 56% identical to PPK1_PSEAE: Polyphosphate kinase (ppk) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K00937, polyphosphate kinase [EC: 2.7.4.1] (inferred from 93% identity to kko:Kkor_0883)

Predicted SEED Role

"Polyphosphate kinase (EC 2.7.4.1)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism or Purine conversions (EC 2.7.4.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.4.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (711 amino acids)

>B158DRAFT_2312 polyphosphate kinase 1 (Kangiella aquimarina DSM 16071)
MGSAAGKSSTVNIDDRAQQTALSMDDLNKMSLNNPEYYLNRELSLLAFNWRVLQQALDQS
IPLLERMRFIFICSNNLDEFFEVRVAGLRHSLARGEARPGLNGLSTEEVLRQVNEQAHKL
VEEQYRIFNQELLPKLAEENIHFLSPKHWDDEQYKWLKKYFKQQVTPVISPISLDLTHPF
PRLVNKSLHFLLHLHGNDAFGRDLEFAVLHMPRSLPRIIELPEKIGGSDGHNFVYLSAII
SEFAEDLFPGMEISGCYQFRLTRDSDLLLEEKGIEDLASALKRELQSRNFGAAVRLEVGE
SCPNKIVNFLLQKCNLTADDLYRVNGPVNLNRLISLPDLVERPDLKFSGFTPKVPDDIQR
RGVFDVVTERDVLLHHPYQSFQPVIDFVRQAASDPEVLAIKQTLYRTGSQSAIVEALIEA
SQSGKEVTAVVELRARFDEASNIELAQKLQEAGVLVVYGVVGYKTHAKMTLVVKREKKHL
TRFAHLGTGNYHAGNARLYTDYSLLTSDPEICEDVHKVFQQLTGMGKVYQLHKLWHAPFT
LHDNIMQAIQIETENALAGKKSGIIIKVNSLTDQSLIEALYRASVAGVKVKLIVRGVCCL
RPGIEGISDNIEVISIIGRFLEHSRIYYFYADGSENVYAASADWMERNLYYRVETCFPIL
SDSAKQQVIKELKLMTSERVQSWHLHADGQYHFSHIKNSKKLHDLLLSKLS