Protein Info for B158DRAFT_2131 in Kangiella aquimarina DSM 16071

Annotation: preprotein translocase, SecA subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 902 PF07517: SecA_DEAD" amino acids 5 to 399 (395 residues), 453.8 bits, see alignment E=7.6e-140 TIGR00963: preprotein translocase, SecA subunit" amino acids 26 to 817 (792 residues), 1147.2 bits, see alignment E=0 PF00270: DEAD" amino acids 97 to 214 (118 residues), 33.9 bits, see alignment E=8e-12 PF01043: SecA_PP_bind" amino acids 230 to 356 (127 residues), 143.2 bits, see alignment E=1.4e-45 PF21090: P-loop_SecA" amino acids 415 to 614 (200 residues), 313.3 bits, see alignment E=2.1e-97 PF07516: SecA_SW" amino acids 616 to 829 (214 residues), 239.2 bits, see alignment E=1.3e-74 PF02810: SEC-C" amino acids 881 to 899 (19 residues), 39 bits, see alignment (E = 1.7e-13)

Best Hits

Swiss-Prot: 69% identical to SECA_ALTMD: Protein translocase subunit SecA (secA) from Alteromonas mediterranea (strain DSM 17117 / CIP 110805 / LMG 28347 / Deep ecotype)

KEGG orthology group: K03070, preprotein translocase subunit SecA (inferred from 69% identity to amc:MADE_03250)

Predicted SEED Role

"Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (902 amino acids)

>B158DRAFT_2131 preprotein translocase, SecA subunit (Kangiella aquimarina DSM 16071)
MSFLSKIFGSRNERTLKKLRKTVELINQLEPEMEALSDEELKAKTTEYKERIEKGETLDQ
LLPEAFATVREASKRTLGLRHFDVQLIGGMVLHGGRVAEMRTGEGKTLVATLPVYLNALS
GKGVHVITVNDYLAQRDANWMKPVYNFLGMDVGVILSGQTHEEKQKAYSADITYGTNNEY
GFDYLRDNMAFQKEHRVQRDLNFAVIDEVDSILIDEARTPLIISGPTEDSSEMYRAIDKL
IPKLEQQEHESEEGEEDTGHYTVDEKSKQAHLTEKGQEYIEELLRQNGLLPAEQSLYSPA
SIALLHHVNAALRAHKLFKKDVDYVVKDGQVVIVDEHTGRTMPGRRWSDGLHQAIEAKEQ
VQIQNENQTLASITFQNYFRLYNKLSGMTGTADTEATELHMIYGLDVVVIPTNKPMQRDD
KGDLIFLTKQEKYAAIIEEIKELQAKGQPVLVGTVSIESSELISKELKKAKIKHQVLNAK
FHAKEADIIAQAGRPGTVTIATNMAGRGTDIVLGGNLQADIDALGENPTAEQIAKAKEEW
EKRHQAVLDAGGLAIIGTERHESRRIDNQLRGRSGRQGDPGLSRFYLSLEDDLMRIFASE
RLGMMMQRLGWDEGEALEHKMVSRAIENAQRKVEQRNFDTRKNLLEYDDVANDQRRVIYE
QRNELMDSDDISDTIADLRDDVVYSIISEYIPPQSIEEMWDVKGLEQRLEQDFVIELPLQ
QWLDEDDKLAEEGLRQRIHEAVEKAYQEKEALLPDPRMMRQLEKQVMLQELDRHWKEHLA
NMDHLRQGIWMRSHAQKNPKQEYKREAFDLFASMLDNLKEDVITLLAKVRFQMPEEVEAM
KRTEVNQAGMQAQHESASALPQSDTARQAETFVREQPKVGRNEPCPCGSGKKFKQCHGKI
ES