Protein Info for B158DRAFT_1423 in Kangiella aquimarina DSM 16071

Annotation: succinate dehydrogenase and fumarate reductase iron-sulfur protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 232 PF13085: Fer2_3" amino acids 2 to 106 (105 residues), 116 bits, see alignment E=1.6e-37 TIGR00384: succinate dehydrogenase and fumarate reductase iron-sulfur protein" amino acids 5 to 224 (220 residues), 290 bits, see alignment E=5.5e-91 PF13183: Fer4_8" amino acids 140 to 214 (75 residues), 41.1 bits, see alignment E=4.3e-14 PF13534: Fer4_17" amino acids 142 to 215 (74 residues), 37.8 bits, see alignment E=4.4e-13 PF13237: Fer4_10" amino acids 142 to 211 (70 residues), 37.7 bits, see alignment E=3.3e-13

Best Hits

Swiss-Prot: 76% identical to SDHB_ECOLI: Succinate dehydrogenase iron-sulfur subunit (sdhB) from Escherichia coli (strain K12)

KEGG orthology group: K00240, succinate dehydrogenase iron-sulfur protein [EC: 1.3.99.1] (inferred from 97% identity to kko:Kkor_1542)

MetaCyc: 76% identical to succinate:quinone oxidoreductase, iron-sulfur cluster binding protein (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1)" in subsystem Serine-glyoxylate cycle or Succinate dehydrogenase or TCA Cycle (EC 1.3.99.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.99.1

Use Curated BLAST to search for 1.3.99.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (232 amino acids)

>B158DRAFT_1423 succinate dehydrogenase and fumarate reductase iron-sulfur protein (Kangiella aquimarina DSM 16071)
MKFSIYRYNPETDKKPYMQEYDLDVPEGSDMMLLDALVALKNQDPTLSFRRSCREGVCGS
DGMNINGKNGLACITALSSLKAPIVIRPLPGLPVIRDLVVDMAQFYKQYEKIKPFLIAND
EPPAKERLQSPEDRAKLDGLYECILCACCSTSCPSFWWNPDKFVGPAGLLQAYRFLIDSR
DTQTEERLAELDDAYSVFRCRGIMNCVDVCPKGLNPTRAIGHIRSMLLKSGV