Protein Info for B158DRAFT_1393 in Kangiella aquimarina DSM 16071

Annotation: sulfur relay protein TusD/DsrE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 130 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details TIGR03012: sulfur relay protein TusD/DsrE" amino acids 4 to 129 (126 residues), 150.7 bits, see alignment E=9.5e-49 PF02635: DsrE" amino acids 6 to 129 (124 residues), 82.6 bits, see alignment E=1.3e-27

Best Hits

Swiss-Prot: 46% identical to DSRE_ALLVD: Putative sulfurtransferase DsrE (dsrE) from Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D)

KEGG orthology group: K07235, tRNA 2-thiouridine synthesizing protein D [EC: 2.8.1.-] (inferred from 89% identity to kko:Kkor_1576)

MetaCyc: 46% identical to DsrE (Allochromatium vinosum)

Predicted SEED Role

"tRNA 5-methylaminomethyl-2-thiouridine synthase TusD"

Isozymes

Compare fitness of predicted isozymes for: 2.8.1.-

Use Curated BLAST to search for 2.8.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (130 amino acids)

>B158DRAFT_1393 sulfur relay protein TusD/DsrE (Kangiella aquimarina DSM 16071)
MATFSLLVTANPYSSQGQFSAIEFARTLLEQGHNLLRVFFYADGVLVASRLHAPPADEIN
LTKSWAKLAIEKDIELIACVTAANKRGIVNASEAERNALTGDNLDPAFEISGLGQLTEAM
LESDRVITFG