Protein Info for B158DRAFT_1284 in Kangiella aquimarina DSM 16071

Annotation: DNA-binding winged-HTH domains

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1070 transmembrane" amino acids 558 to 578 (21 residues), see Phobius details PF00486: Trans_reg_C" amino acids 28 to 102 (75 residues), 60.7 bits, see alignment 3.7e-20 PF20703: nSTAND1" amino acids 122 to 511 (390 residues), 92.9 bits, see alignment E=1e-29 PF13181: TPR_8" amino acids 888 to 915 (28 residues), 13.8 bits, see alignment (E = 1.6e-05) amino acids 935 to 962 (28 residues), 14.3 bits, see alignment (E = 1.1e-05)

Best Hits

Predicted SEED Role

"Adenylate cyclase (EC 4.6.1.1)" in subsystem cAMP signaling in bacteria (EC 4.6.1.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.6.1.1

Use Curated BLAST to search for 4.6.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1070 amino acids)

>B158DRAFT_1284 DNA-binding winged-HTH domains (Kangiella aquimarina DSM 16071)
MENSPIQIGEWLVDVESHQMQRLDDATQQVIFEPKVMNVLACLIEHAGQVVSSEVLLDRC
WPNQFLSDNPLHKCITQLRKAFKDSSRNPTYIQTIPKRGYRLIAQISSEPDNNQITDIDI
IPYPGTRSFAYSESRLFYGRDYAVQELLYIMKQPATSFTKNCVLVVGESLVGKTSLIHAG
LRPELEQQEIEFQYIDAISSQSDYDQQLKALEAITRIEDDKGGKVSKPTVILFDHIELAV
MLREEQQEHAHDVSDFKNRVKQLLDLALKLYANPNVKLLICLNPFNLGLLKKFSAYQSIV
DNAHLYTVNRPASTDVYLAITQPAINSGYTFKTCPKTGKTLAQELHKLYVKNQLTLKQLQ
GLLLELCQRSPDKQLSFDIYNQIKRERTDLWMNRQSHIRNEINTNTKALDPLLAILIKVN
FDGAFHIKLTEIQLDTIQNNEMLRLVGELISNDLLSCYIKNNESYIRFISQSVIHALPFT
QQWINKHYQSLITKEHISANCELWKTHNQSSGYLLSPGKPLEDARQLMELKGKELAQPHK
DYIRASLKAEKRKNRIKSIMVAAVCILSLTSTSALLVANNARISQQNARNNAEQLIAFMN
QELKRELIPLGKLDLMESLGIEIINYFNSSGIDSSSAQLHNAMAQRLLGEVYTQQGHHDK
ANHFFEQATSLLNTLVESQLESSSLYNDIIYELGQVSYWQGYLSYLNNDYSQTRHYWEAY
FNHSTQLIVLSPENSRYLNELSYAHNNLGTLELLEHEYQDALHHFEQSAELKQRLLKESN
LDITTELVDTYSWIARTYDYLGETHKSRAQYQKQLETLLALKQQQDINKAQQYYLAVAYQ
NLANLNFVLNDIQPSLAQLNSSLLLLDELISYEPTNVEYQESKVFTLIMQGQLYRIQGQY
DLAQLQLNKALTLNQSLQPETIGHASQKAEFYQSKIYYELGRYHQAQGYIKSADDYYQKA
LTQNIQKSGDSYHQELFALLHLRTAELKMAQKRDQTITDSIRSELQMAEQIFEQLTKNNR
SLRYQLPFCQIKHYLKKQAVNKCSTTEGGTLSVLDTHPEYNNLFETPIAN