Protein Info for B158DRAFT_0827 in Kangiella aquimarina DSM 16071

Annotation: acyl-phosphate glycerol 3-phosphate acyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase
  • amino acids 8 to 194 (187 residues), 206 bits, E=2.4e-65
• PF02660: G3P_acyltransf
  • amino acids 11 to 184 (174 residues), 172.1 bits, E=5.4e-55

Best Hits

Swiss-Prot: 46% identical to PLSY_PASMU: Glycerol-3-phosphate acyltransferase (plsY) from Pasteurella multocida (strain Pm70)

KEGG orthology group: K08591, glycerol-3-phosphate acyltransferase PlsY [EC: 2.3.1.15] (inferred from 91% identity to kko:Kkor_2167)

Predicted SEED Role

"Acyl-phosphate:glycerol-3-phosphate O-acyltransferase PlsY" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria

MetaCyc Pathways

• phosphatidylglycerol biosynthesis I (6/6 steps found)
• phosphatidylglycerol biosynthesis II (6/6 steps found)
• superpathway of phospholipid biosynthesis III (E. coli) (10/12 steps found)
• CDP-diacylglycerol biosynthesis I (4/4 steps found)
• CDP-diacylglycerol biosynthesis II (4/4 steps found)
• superpathway of cardiolipin biosynthesis (bacteria) (10/13 steps found)
• oleate biosynthesis III (cyanobacteria) (2/3 steps found)
• phosphatidate biosynthesis (yeast) (3/5 steps found)
• diacylglycerol and triacylglycerol biosynthesis (3/7 steps found)
• palmitoyl ethanolamide biosynthesis (2/6 steps found)
• superpathway of stearidonate biosynthesis (cyanobacteria) (2/6 steps found)
• stigma estolide biosynthesis (2/7 steps found)
• anandamide biosynthesis II (2/8 steps found)
• anandamide biosynthesis I (4/12 steps found)
• superpathway of phospholipid biosynthesis II (plants) (11/28 steps found)

KEGG Metabolic Maps

• Glycerolipid metabolism
• Glycerophospholipid metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.15

Use Curated BLAST to search for 2.3.1.15

Protein Sequence (201 amino acids)

>B158DRAFT_0827 acyl-phosphate glycerol 3-phosphate acyltransferase (Kangiella aquimarina DSM 16071)
MEWQLAGLWLLAYLTGSISSAVIVCRIMGLPDPRKFGSHNPGATNVLRLGGKKAAIFTLL
GDMLKAIIPILIGYALDLHNRNLGWVGFMAFIGHLYPIYFRFKGGKGMATYFGALVALSP
LLLAYCIVTWLVTAFFTRYASLASILSSFAVAAFGFYLDHKYFFPLFAMFLILTARHHRN
IRNLWQGTERKITDKRSNDSQ