Protein Info for B158DRAFT_0282 in Kangiella aquimarina DSM 16071

Annotation: Uncharacterized membrane protein (homolog of Drosophila rhomboid)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 199 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 57 to 78 (22 residues), see Phobius details amino acids 90 to 110 (21 residues), see Phobius details amino acids 121 to 139 (19 residues), see Phobius details amino acids 151 to 171 (21 residues), see Phobius details amino acids 175 to 194 (20 residues), see Phobius details PF01694: Rhomboid" amino acids 46 to 195 (150 residues), 80.5 bits, see alignment E=7.1e-27

Best Hits

KEGG orthology group: K02441, GlpG protein (inferred from 95% identity to kko:Kkor_0137)

Predicted SEED Role

"GlpG protein (membrane protein of glp regulon)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (199 amino acids)

>B158DRAFT_0282 Uncharacterized membrane protein (homolog of Drosophila rhomboid) (Kangiella aquimarina DSM 16071)
MLKDFLSQAGWMTKTLVGISILVSILTMSGTNEYTYWFAFNWNLILQGEVHRLITPIFLH
FMIGAFPIHLLFNMMWLWDQGGSIEKARSAWYLLVIVLITGVASNVGEYFSSVYFGYGRS
YLFGGMSGVVYGLLGFNFVRRRFDPFFPVHVHPGLMQFMLLWLVLGFTGLLGNIANAAHL
IGLLSGGLLGYITAKTRAF