Protein Info for B158DRAFT_0152 in Kangiella aquimarina DSM 16071

Annotation: Membrane-associated lipoprotein involved in thiamine biosynthesis

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 PF02424: ApbE" amino acids 38 to 294 (257 residues), 206.7 bits, see alignment E=2.5e-65

Best Hits

KEGG orthology group: K03734, thiamine biosynthesis lipoprotein (inferred from 90% identity to kko:Kkor_0261)

Predicted SEED Role

"Thiamin biosynthesis lipoprotein ApbE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (301 amino acids)

>B158DRAFT_0152 Membrane-associated lipoprotein involved in thiamine biosynthesis (Kangiella aquimarina DSM 16071)
MNEALHTIAYKTSQGFVTGHFTAMAGPCEVIIETSDQELAEKVTQTVADEAWRIESTFSR
YRTDNIIYRINNADGDPVEVDAETARLLDFADLCFEVSDGMFDITSGVLGKIWKFDGSSN
VPYQNDIDKLLPKIGWQKVSWTNPRLQMPAGMALDFGGIGKEYAVDSAAQLARQITELPI
LINFGGDIVATAPPVSREHWLIGIEPLALGQNTVPPQVALKHGGVATSGDSKRYLLHNNK
VLSHVLNPKTGWPVADAPASVTVLASNCTQAGMLSTLAMLQGKEAETFLQSQEVEHWIQR
R