Protein Info for B158DRAFT_0005 in Kangiella aquimarina DSM 16071

Annotation: diguanylate cyclase (GGDEF) domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 375 transmembrane" amino acids 21 to 41 (21 residues), see Phobius details amino acids 52 to 72 (21 residues), see Phobius details amino acids 80 to 97 (18 residues), see Phobius details amino acids 99 to 117 (19 residues), see Phobius details amino acids 123 to 141 (19 residues), see Phobius details amino acids 161 to 183 (23 residues), see Phobius details PF20969: MASE11" amino acids 24 to 184 (161 residues), 28.1 bits, see alignment E=1.8e-10 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 202 to 361 (160 residues), 136.5 bits, see alignment E=3.7e-44 PF00990: GGDEF" amino acids 205 to 360 (156 residues), 138.9 bits, see alignment E=1.3e-44

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (375 amino acids)

>B158DRAFT_0005 diguanylate cyclase (GGDEF) domain (Kangiella aquimarina DSM 16071)
MSDKSLSPIAIKWQLILDQSMDRLIILLALCTVPAVISSLARIPEMGFQPSMLFHIVVGL
LMIIIAVFRNILSFHVKTNVVLTLSVTISVVGLWDWGLVGNGFVWMLLSASLFALIYGSR
AVFIFNALFIAYSAVVAYLYINGNLSVPVSQSQYSQSLSAWSTAIIGAAMPLIIVSYAII
ALVKKAGLLIIALEDQKQQATHLAERDPLTGLYNLRVLNNRLEHAINLAQRQPMQIYLLN
IDLDDFKRINDQYGHAAGDVALEYVAKTLVKVTRESDTVCRVGGDEFLILIDTALEVPVK
QIVYRIRHELSTQITFEGHTFPIEASIGVAEYNHNSHEEISSDRMIRLADQAMYKEKASR
KLKKLSQGKPDPALQ