Protein Info for Atu6172 in Agrobacterium fabrum C58

Annotation: component of type IV secretion system

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 295 transmembrane" amino acids 35 to 54 (20 residues), see Phobius details amino acids 65 to 84 (20 residues), see Phobius details amino acids 161 to 186 (26 residues), see Phobius details amino acids 198 to 220 (23 residues), see Phobius details amino acids 226 to 245 (20 residues), see Phobius details amino acids 253 to 275 (23 residues), see Phobius details PF04610: TrbL" amino acids 43 to 232 (190 residues), 57 bits, see alignment E=1.2e-19

Best Hits

Swiss-Prot: 100% identical to VIRB6_AGRFC: Protein VirB6 (virB6) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K03201, type IV secretion system protein VirB6 (inferred from 100% identity to atu:Atu6172)

Predicted SEED Role

"Inner membrane protein of type IV secretion of T-DNA complex, VirB6"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P17796 at UniProt or InterPro

Protein Sequence (295 amino acids)

>Atu6172 component of type IV secretion system (Agrobacterium fabrum C58)
MNFTIPAPFTAIHTIFDLAFTTSLDTMLGTIQEAVSAPLVACVTLWIIVQGILVMRGEID
TRGGITRVITVTVVVALVVGQANYHDYVVSVFEETIPNFIQQFSGSGLPLQTIPAQLDTM
FALTQAAFQRIASEIGPMNDQDILAFQGAQWVFYGTLWSAFGIYDAVGILTKVLLAIGPL
ILTGYIFDRTRDIAAKWIGQLITYGLLLLLLNLVATIVILTEATALTLMLGVITLAGTTA
AKIIGLYELDMFFLTGDALIVALPAIAGNIGGSYWSGATQSANSLYRRFAQVDRR