Protein Info for Atu6151 in Agrobacterium fabrum C58

Annotation: P-450 monoxygenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 391 PF00067: p450" amino acids 265 to 362 (98 residues), 53.7 bits, see alignment E=8.1e-19

Best Hits

Swiss-Prot: 84% identical to CPXD_RHIRD: Cytochrome P450-pinF2, plant-inducible (cyp104) from Rhizobium radiobacter

KEGG orthology group: K00517, [EC: 1.14.-.-] (inferred from 100% identity to atu:Atu6151)

Predicted SEED Role

"Plant-inducible protein PinF2, cytochrome P450-like, contributes to virulence"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.14.-.-

Use Curated BLAST to search for 1.14.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D2E2 at UniProt or InterPro

Protein Sequence (391 amino acids)

>Atu6151 P-450 monoxygenase (Agrobacterium fabrum C58)
MQLAPVDRVTTIDDLTLDPYPIYRRMRAQTPVVRVASVMRTFLTKASDTKMVKDQPRRFS
SDDPNTPMKPAFQAHTLMRKDGAEHARERMAMAKAFAPKTTAEHWAAIYRDIVNEYLDRL
SRGSTVDLFAEICGPVAARILAHILGISEASDAEMIRWSQRLIEGAGNFGWRPEPFERAN
EANAEMNRLFDNLVEKHRAEPNPSAFAIMVTASDPIPMSQIYANIKIAVGGGINEPRDAL
GTIIYGLLTNPEQFEEVKRQQCWGQVFEEGVRWVAPIQASSRLVLEDTEIRGFLVPKGDT
VMTIQASANRDEDVFDDGERFNVFRQNNAHQSFGSGPHHCAGAQISRQTVGAIMLPTLFE
RFPNMTLTNPDAVQWRGFGFRGPISLPVTLI