Protein Info for Atu6138 in Agrobacterium fabrum C58

Annotation: Repressor of the acc and arc operons

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 258 PF08279: HTH_11" amino acids 9 to 50 (42 residues), 25.6 bits, see alignment 1.8e-09 PF08220: HTH_DeoR" amino acids 9 to 64 (56 residues), 74.7 bits, see alignment E=7.7e-25 PF00455: DeoRC" amino acids 78 to 237 (160 residues), 163.8 bits, see alignment E=6.5e-52

Best Hits

Swiss-Prot: 100% identical to ACCR_AGRFC: Transcriptional repressor AccR (accR) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: None (inferred from 100% identity to atu:Atu6138)

Predicted SEED Role

"Glycerol-3-phosphate regulon repressor, DeoR family" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See P32104 at UniProt or InterPro

Protein Sequence (258 amino acids)

>Atu6138 Repressor of the acc and arc operons (Agrobacterium fabrum C58)
MVFNSTQDRQAKIVELLRDEQFLAIGRLTEHFQISVATARRDLSELHEAGLLRRTHGGAV
SVTQVTQDKPNAARAVWNRAEKAAIAGVVAGMIVEGDTVLLDAGTTALEVAKKLADRRNL
TFISNGLDIVEELTRGEGKSIYSVGGEYTETNRSFRGPLAEQFIRQFNVDKLILNAASID
VDRGLICTSSPVNASVARAMIEVSSRVIVVADHSKFTKSSLSVTARIEDVGVIVTDSGTR
TIIETIPEKLRKKFVVAN