Protein Info for Atu6043 in Agrobacterium fabrum C58

Annotation: replication protein A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 transmembrane" amino acids 265 to 281 (17 residues), see Phobius details TIGR03453: plasmid partitioning protein RepA" amino acids 18 to 404 (387 residues), 646.6 bits, see alignment E=5.8e-199 PF10609: ParA" amino acids 122 to 299 (178 residues), 29.3 bits, see alignment E=1.8e-10 PF06564: CBP_BcsQ" amino acids 122 to 315 (194 residues), 36.8 bits, see alignment E=9.6e-13 PF13614: AAA_31" amino acids 122 to 298 (177 residues), 124.2 bits, see alignment E=1.8e-39 PF09140: MipZ" amino acids 123 to 160 (38 residues), 30.4 bits, see alignment 7.7e-11 PF01656: CbiA" amino acids 124 to 366 (243 residues), 89.2 bits, see alignment E=6.5e-29 PF02374: ArsA_ATPase" amino acids 130 to 273 (144 residues), 34.2 bits, see alignment E=4.9e-12

Best Hits

Swiss-Prot: 57% identical to REPA_AGRRH: Putative replication protein A (repA) from Agrobacterium rhizogenes

KEGG orthology group: None (inferred from 100% identity to atu:Atu6043)

Predicted SEED Role

"Plasmid replication protein RepA" in subsystem Plasmid replication

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D2P0 at UniProt or InterPro

Protein Sequence (405 amino acids)

>Atu6043 replication protein A (Agrobacterium fabrum C58)
MSKAAAISRNDRPSVDVTIGEHAEQLSSQLQAMSEALFPPTSHKSLRKFTSGEAARLMKI
SDSTLRKMTLAGEGPQPELASNGRRFYTLGQINEIRQMLAGSTRGRESIDFVPHRRGSEH
LQVVAVTNFKGGSGKTTTSAHLAQYLALQGYRVLAVDLDPQASLSALLGVLPETDVGANE
TLYAAIRYDDTRRPLRDVIRPTYFDGLHLVPGNLELMEFEHTTPKALTDKGTRDGLFFTR
VAQAFDEVADDYDVVVIDCPPQLGFLTLSGLCAATSMVITVHPQMLDIASMSQFLLMTRD
LLGVVKEAGGNLQYDFIRYLLTRYEPQDAPQTKVTALLRNMFEDHVLTNPMVKSAAVSDA
GLTKQTLYEIGRENLTRSTYDRAMESLDAVNSEIEALIKMAWGRV