Protein Info for Atu5537 in Agrobacterium fabrum C58

Annotation: mercuric reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 453 PF07992: Pyr_redox_2" amino acids 4 to 314 (311 residues), 214.9 bits, see alignment E=5.1e-67 PF13738: Pyr_redox_3" amino acids 7 to 302 (296 residues), 46.2 bits, see alignment E=1.2e-15 PF00070: Pyr_redox" amino acids 171 to 246 (76 residues), 68 bits, see alignment E=2.6e-22 PF02852: Pyr_redox_dim" amino acids 342 to 445 (104 residues), 84.7 bits, see alignment E=1.6e-27

Best Hits

KEGG orthology group: K00520, mercuric reductase [EC: 1.16.1.1] (inferred from 100% identity to atu:Atu5537)

Predicted SEED Role

"PF00070 family, FAD-dependent NAD(P)-disulphide oxidoreductase" in subsystem Mercuric reductase

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.16.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CL23 at UniProt or InterPro

Protein Sequence (453 amino acids)

>Atu5537 mercuric reductase (Agrobacterium fabrum C58)
MKEYDAIFIGAGQAGPFLAARMAAMGRKVVLIERKFLGGTCVNAGCMPTKTLVASAKTAQ
VARRASEFGVRIDGEPVVDMKAVAARARKVTLDARSGLASWFDSLETMDVVYGHARFVGA
KVVSVGGSLYTAPQIFINVGARPHIPDVPGLANVPYLTSTSVIALEELPKHLVVLGGSYI
GLEFAQMYRRFDAQVTVIERGQYLASREDEDISQAIADILTRDGIKVLLSHKIVSVTTDS
AEITVRTDQGDVRGSHVLVAVGRQPNTDDLGLDQAGVETDRRGYITVDERLQTNVEGIWA
LGDCNGRGAFTHTSYNDFEIAAANLLDGGDRKVSDRILGYGLYIDPPLGRVGMTERQAKE
AGHRIKVATRPMNRVGRAVEKGETLGLMKLVTEADTDRVLGAAFLGVGGDEAVYGVLDAM
NLGATTEKLRWAVPIHPTVGELVPTLISDLKET