Protein Info for Atu5481 in Agrobacterium fabrum C58

Annotation: ABC transporter membrane spanning protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 242 transmembrane" amino acids 18 to 43 (26 residues), see Phobius details amino acids 55 to 75 (21 residues), see Phobius details amino acids 81 to 101 (21 residues), see Phobius details amino acids 121 to 142 (22 residues), see Phobius details amino acids 189 to 210 (22 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 12 to 109 (98 residues), 105.8 bits, see alignment E=6.8e-35 PF00528: BPD_transp_1" amino acids 33 to 215 (183 residues), 79.7 bits, see alignment E=1.2e-26

Best Hits

Swiss-Prot: 36% identical to YECS_ECOLI: L-cystine transport system permease protein YecS (yecS) from Escherichia coli (strain K12)

KEGG orthology group: K02029, polar amino acid transport system permease protein (inferred from 100% identity to atu:Atu5481)

MetaCyc: 36% identical to cystine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Ribose ABC transport system, permease protein RbsC (TC 3.A.1.2.1)" in subsystem D-ribose utilization (TC 3.A.1.2.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CL49 at UniProt or InterPro

Protein Sequence (242 amino acids)

>Atu5481 ABC transporter membrane spanning protein (Agrobacterium fabrum C58)
MSLDLVFDYVFSPAFFHGALLTLVITVTSLFFGMIAGLIVALLQESRIRPLQIFTLVYLW
LFRGTPVLFQIIFIYNVLPTFGVMLSAFVSAVIALSLNEGAYMAEIIRSGLQAVKKGQRT
AGLALGMTRFAVMCYIVIPQAARIVLPPTGNQMIGMLKTSALVSVVAVEELLLVANQTAS
SNFKYFEALTAAGIYYLALTSIFMGFQYLLERALDRKRPRGKRRSVSLMARLAALTAKTD
AR