Protein Info for Atu5466 in Agrobacterium fabrum C58

Annotation: potassium uptake protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 637 transmembrane" amino acids 19 to 40 (22 residues), see Phobius details amino acids 60 to 82 (23 residues), see Phobius details amino acids 105 to 127 (23 residues), see Phobius details amino acids 147 to 165 (19 residues), see Phobius details amino acids 172 to 194 (23 residues), see Phobius details amino acids 213 to 240 (28 residues), see Phobius details amino acids 253 to 273 (21 residues), see Phobius details amino acids 293 to 320 (28 residues), see Phobius details amino acids 345 to 366 (22 residues), see Phobius details amino acids 372 to 393 (22 residues), see Phobius details amino acids 403 to 425 (23 residues), see Phobius details amino acids 431 to 449 (19 residues), see Phobius details PF02705: K_trans" amino acids 22 to 471 (450 residues), 564.3 bits, see alignment E=1.7e-173 PF22776: K_trans_C" amino acids 489 to 637 (149 residues), 156.4 bits, see alignment E=4.8e-50

Best Hits

Swiss-Prot: 100% identical to KUP2_AGRFC: Probable potassium transport system protein kup 2 (kup2) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K03549, KUP system potassium uptake protein (inferred from 100% identity to atu:Atu5466)

Predicted SEED Role

"Kup system potassium uptake protein" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8UJL0 at UniProt or InterPro

Protein Sequence (637 amino acids)

>Atu5466 potassium uptake protein (Agrobacterium fabrum C58)
MTSSNSTVPDSRSETKKFLVLLLGSIGVVYGDIGTSPLYAFRESLRPFTANGVQHEHVVG
LISLMIWTLTIIVTFKYVLFLLRADNDGEGGTLSLLALLMKKTGSYMPVLFFAGLIGSAL
FIGDAMITPALSVMSALEGMKLVTPAFSDYVLPLSALIMVGLFAVQSKGTGAVAVFFGPI
TVVWFLAMAWGGLIHIGDDWTILEAVNPINALWFITHAGWAGLIVLGAVFLTVTGAEALY
ADLGHFGRKPISVAWFILVFPALALNYLGQGALVLSNPAAIENPFYLLYPEWALFPMIIL
ATMATVIASQAVITGAFSLARQAVHLGFLPKLMIRFTSETNTGQIYVPAVNMVLFIGVLV
LIFSFGDSESLATAYGISVTGAMVVTTLMAFQFLRSIRGKSAFTAAILLAPLFSIEAVFL
AANLLKVHDGGWVPLALAGVIILVMWTWTKGSRYLREKISKNDVSLDTFITSLERSISRE
SRSAPVLVSGTAVFLTSVPDKAPSVLLHNLKHNHVLHEQNVILTIWTHDKPYVADTDRVE
ITRISKHFMRLDINFGFMDDPNVVKALPLCKKKGFKFEIMQTSFYLGRRNLIATPNTGLP
RWQEDLYIALADFGVDPSAYFKLPPNRVIEIGEQVAI