Protein Info for Atu5464 in Agrobacterium fabrum C58

Annotation: IclR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 560 PF09339: HTH_IclR" amino acids 11 to 62 (52 residues), 49.8 bits, see alignment 3.6e-17 PF01614: IclR_C" amino acids 79 to 248 (170 residues), 117.7 bits, see alignment E=6.4e-38 PF08450: SGL" amino acids 284 to 526 (243 residues), 307 bits, see alignment E=1.6e-95

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu5464)

Predicted SEED Role

"Transcriptional regulator, IclR family / Gluconolactonase family protein" in subsystem Homogentisate pathway of aromatic compound degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D306 at UniProt or InterPro

Protein Sequence (560 amino acids)

>Atu5464 IclR family transcriptional regulator (Agrobacterium fabrum C58)
MKPETPGGTAALAKGLTLLDMVADAPEPPRFAELLRASGLPKPTFARILRTLIAYGLVRQ
DEARGTYVLGQRFLEMSHKVWESFDLVSAATPELERLAAELGETVALCRLDGTMTQYLAE
RSPNGLSVRVEVGRRVPLHCTAPGKALLAFQDPAVGRALLDRLTLDLQTAKTITTLDALQ
ADLTLTRARGYSISYEEHLPGVNSVAAPVMGRDNTPMGVLVALGPSSRLDSSNIHPAGRE
LIAAARRITGAAGAVAISSRPRPRSATGRPSAELSCILPWGAQLGESPVWHEGEDALYWV
DILHPAVHRFDPATGRNETCETGKLVSAVIPVTGGRLLVASQDGVEWLDFASGRLTPFVS
PEAGIADNRLNDAKCGPDGAIWVGSMRIDASKPTGALYRINANGASERKEGGIIVSNGLG
WSPDGRTFYFVDTVPGLIHAYDCDPATGALSQRREFARIPVADGRPDGLAVDAEGGVWCA
IWDGWCVRRYLPNGKLDQVIDMPVPRPSSIAFGGPDLSTLFITSARTRLPASTLADAPLS
GGLFSCRPGISGARIAMFEG