Protein Info for Atu5414 in Agrobacterium fabrum C58

Annotation: Xaa-Pro dipeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 474 PF00557: Peptidase_M24" amino acids 203 to 453 (251 residues), 96 bits, see alignment E=1.4e-31

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu5414)

Predicted SEED Role

"Proline dipeptidase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CL85 at UniProt or InterPro

Protein Sequence (474 amino acids)

>Atu5414 Xaa-Pro dipeptidase (Agrobacterium fabrum C58)
MNITATRAGAYRIGSLLADFQPDFDFAAPLPLPVAEFEDRLSRIRRQAVEAGHDALIVHT
GGVGWFHTSNHYLRYICDWMREGVLIIPTDVDKPMVLLSFFTQSVLLPPGGEPVLLEDIW
QIGPIGREYADRPGDSVIKTAEKCAELLGNMGLSKAQIGRIGDRTSLTFWAGLDELMPRV
KFVADNAILDRMQKVRSPREIEMFRAAAQLVSIATQAAYHVAKPGVTDHEIYAAFTQAQL
SFGGETGDGYQIGINEFGTHCGKPYGHVVRPGDLINLYVSNVTYRGYTAQTARMIAIGEI
TKRQEEVLAACTEGVKRAEKLIRPGALMRDINNAAFEPMIEHGMLASPEARTMPYNWAPM
DDGSARLIPRQYVKNIDWEAQGRTLMHVYPATHGPHNPNLGHSVGMAGGQNSFNISSHNY
DRMEEGMVFVLHTQWLEPLSAGCNVGDMYVVTKGGFENLSRHTPLETHRIAAEI