Protein Info for Atu5302 in Agrobacterium fabrum C58

Annotation: aminotransferase, class III

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 70% identical to DGDA_BURCE: 2,2-dialkylglycine decarboxylase (dgdA) from Burkholderia cepacia

KEGG orthology group: K00596, 2,2-dialkylglycine decarboxylase (pyruvate) [EC: 4.1.1.64] (inferred from 100% identity to atu:Atu5302)

Predicted SEED Role

"Siderophore biosynthesis diaminobutyrate--2-oxoglutarate aminotransferase (EC 2.6.1.76)" (EC 2.6.1.76)

MetaCyc Pathways

ectoine degradation (3/4 steps found)
ectoine biosynthesis (3/5 steps found)
norspermidine biosynthesis (3/6 steps found)
superpathway of polyamine biosynthesis III (3/8 steps found)
rhizobactin 1021 biosynthesis (1/7 steps found)
pyoverdine I biosynthesis (2/11 steps found)
baumannoferrin biosynthesis (1/11 steps found)

KEGG Metabolic Maps

Glycine, serine and threonine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.76 or 4.1.1.64

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CLE1 at UniProt or InterPro

Protein Sequence (435 amino acids)

>Atu5302 aminotransferase, class III (Agrobacterium fabrum C58)
MSLNNEQSFWNQANRHLTRYGPSFESIIVERASGSYVYDANDRPILDFTSGQMSALLGHT
HPDIVATVDRQMRSVAHLFSGMLSRPVVELASRLAALAPGLDRVQLLTTGAESNEAAIRM
AKLVTGGHEVVAFAQSWHGMTGAAAAATYSAGRRGYGPVAAGSLVIPAPNSYRPRFAKPD
GTNDWQTELDDAFALIDNQSTGSLAAFIAEPILSSGGILELPAGYLAALKLKCEERGMLL
ILDEAQTGVGRTGHMFAFQRDGVTPDILTLSKTLGAGLPLAAVMTTEAIEQKAFEKGYLF
YTTHVSDPLLAAVGVTVLDVVEREGLLAAAIGRGARLRAGLVSLQQRFECVGDVRGRGLL
MGLEIVADRQTKAPGFALGAKIMEEAMRRGLSMNIVKLPGMGGVFRIAPPLTVSDEEIDH
GIEIMSDSIQAASGA