Protein Info for Atu5248 in Agrobacterium fabrum C58

Annotation: ABC transporter nucleotide binding/ATPase (spermidine/putrescine)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 376 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF00005: ABC_tran" amino acids 45 to 187 (143 residues), 111.2 bits, see alignment E=9.5e-36 PF08402: TOBE_2" amino acids 299 to 373 (75 residues), 30.7 bits, see alignment E=4.3e-11

Best Hits

KEGG orthology group: K02052, putative spermidine/putrescine transport system ATP-binding protein (inferred from 100% identity to atu:Atu5248)

Predicted SEED Role

"Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1)" in subsystem Polyamine Metabolism (TC 3.A.1.11.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CLH6 at UniProt or InterPro

Protein Sequence (376 amino acids)

>Atu5248 ABC transporter nucleotide binding/ATPase (spermidine/putrescine) (Agrobacterium fabrum C58)
MSLAMISPSLPDTSSTIQAQVQPAPKPVLQLVDVRKIFGDFAAVDGISVDIKEGEFVTIV
GPSGSGKTTLLRMLAGMESPSEGYITLRGEVINSVPADKRPTCLVFQSLALFPHKTVGEN
IEFPLKVRKMPAAERRIRALEFMRMVRLPESYYSKNVMRCSGGEKQRVALARAFAYDPDV
LFFDEPLSALDYKLKKVLEKELKDLHRESGKTFVYITHSLEEAMVMSDRVGVMSRGHLVQ
IGTPEEIYTKPATRFVAEFFGEVNSFEVKRKGEGAWTLADGKPITVAPVAEAIGETATVI
VRPETMRFITGASSADNLISGTIYNEYSLGSRMQYQVHSGDRIYLVEAARSAVSGVSSGD
LVTIGWDASDAIVVGD