Protein Info for Atu5049 in Agrobacterium fabrum C58

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 TIGR02772: Ku protein" amino acids 5 to 255 (251 residues), 278.4 bits, see alignment E=3e-87 PF02735: Ku" amino acids 15 to 194 (180 residues), 157.7 bits, see alignment E=1.6e-50

Best Hits

Swiss-Prot: 62% identical to KU_RHOSK: Non-homologous end joining protein Ku (ku) from Rhodobacter sphaeroides (strain KD131 / KCTC 12085)

KEGG orthology group: K10979, DNA end-binding protein Ku (inferred from 100% identity to atu:Atu5049)

Predicted SEED Role

"Ku domain protein" in subsystem DNA Repair Base Excision

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D415 at UniProt or InterPro

Protein Sequence (298 amino acids)

>Atu5049 hypothetical protein (Agrobacterium fabrum C58)
MVAPRANWKGFIKYGEVACPVALYTAASSSERIAFNTLNRKTGNRVKREFVDSETGDPVE
RDEQVKGYEVENGQYIILEPEEVAAAVPDSDKTLKIDAFIPCHEIDDVYFDKPYYLAPDK
MGTDAFLLLRDGMKKAKVAAIARTVLFRRVRTVLIRPHGKGLIATTLNFDYEVRSSQEAF
EELPDLKIEGEMLELAEHIIGTKKGSFDASAFDDRYEAAVAELVKAKIEGRALPKKKAPP
ASKPSDLLQALRESAGVVAKAASKRTAANVNKGTSRQKVAKAAAAKTKSAASQTRRAG