Protein Info for Atu5000 in Agrobacterium fabrum C58

Annotation: replication protein A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 435 transmembrane" amino acids 293 to 318 (26 residues), see Phobius details TIGR03453: plasmid partitioning protein RepA" amino acids 48 to 434 (387 residues), 608 bits, see alignment E=3.1e-187 PF06564: CBP_BcsQ" amino acids 151 to 327 (177 residues), 27.6 bits, see alignment E=5.2e-10 PF13614: AAA_31" amino acids 151 to 336 (186 residues), 129.5 bits, see alignment E=3.5e-41 PF09140: MipZ" amino acids 152 to 192 (41 residues), 30.2 bits, see alignment 7.2e-11 PF01656: CbiA" amino acids 153 to 390 (238 residues), 78.2 bits, see alignment E=1.4e-25

Best Hits

Swiss-Prot: 48% identical to Y4CK_SINFN: Putative replication protein A (NGR_a00010) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: None (inferred from 100% identity to atu:Atu5000)

Predicted SEED Role

"Plasmid replication protein RepA" in subsystem Plasmid replication

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7D453 at UniProt or InterPro

Protein Sequence (435 amino acids)

>Atu5000 replication protein A (Agrobacterium fabrum C58)
MSGRKARIMLYLWRALGGKPNLARQGGDMAIAKQIEATIGQKEDAGGKIARHASLLSQQL
QELRTRMYPPKSEKSLRPFLTNEVSKLTSIPDSTLKLMSSEGRGPVPGRLENNHRVYTLA
QINELREFFASQKPSEALRFLPRRREGEHLQVVAIANFKGGSAKTTTCVHLAHYLALQGY
RVLALDLDPQASLSALFGAQPEFDVGANETIYAALRYDDAERRPIRDIIRKTYFDGIDLI
PGNLEVMEYEHETPRVLAQKSGSGAIFFERLKLALSEVEQDYDIVILDTPPSLGFLTLSA
IYAATSMIITVHPAMLDVASMSQFLLMMGDLISVLNESGAQLDQDFIRYLVTRHDPNDAP
QSQVVAMMRHLFGSDVLLPTLIESTAVEAAGLAKRSIYELEMGQIGRDTHKRAREAVDAV
NEAILKLINTSWGRT