Protein Info for Atu4822 in Agrobacterium fabrum C58

Annotation: acyl-CoA synthetase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 546 PF00501: AMP-binding" amino acids 29 to 396 (368 residues), 269.5 bits, see alignment E=4.2e-84 PF13193: AMP-binding_C" amino acids 446 to 521 (76 residues), 61.4 bits, see alignment E=1.3e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu4822)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CH67 at UniProt or InterPro

Protein Sequence (546 amino acids)

>Atu4822 acyl-CoA synthetase (Agrobacterium fabrum C58)
MTMQSAVQHPAGGVAPSTTRVMNLSHFLTQAARRNPDHIGFVWGEKTWSWAQMEARVDAM
AHALETEFGVRKGDRILVQSSNNNQMFESMFACFRVGAVWVPTNYRQSPDEVAYLAKASG
ARGMICASAFPDHAKASHEASTIDFSIAIGTAEFGEDYDAIVARHMGRKVKSQAVDRDDP
CWFFFTSGTTGRPKAAVLTHGQMAFVITNHLCDLMPGTGPDDASIVVAPLSHGAGIHQLV
QVAHGAKTVLPAAEKLDVPAVWALIEKWRITNAFTVPTILKMLVEDPSVDRFDHSSLRYV
IYAGAPMYRADQKRALAKLGPVLVQYFGLGEVTGNITVLPPSFHNAEDGPETRVGTCGFD
RTGMEVQIQNDAAEEVGAGETGEICVIGPAVFAGYYDNPEANAKAFRNGWFRTGDLGHRD
ENGFLYITGRASDMYISGGSNIYPREIEEKILMHPDISETAVLGVPDAVWGEVGVAVCVA
REGADIAAIDLKAYLEGKMARYKLPKSVVFWDAMPKSAYGKITKKMIREELEKRGQMPAF
EEKRTG