Protein Info for Atu4778 in Agrobacterium fabrum C58

Annotation: non-heme chloroperoxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details PF00561: Abhydrolase_1" amino acids 72 to 309 (238 residues), 108.8 bits, see alignment E=7.2e-35 PF12697: Abhydrolase_6" amino acids 73 to 308 (236 residues), 69.8 bits, see alignment E=1.2e-22 PF12146: Hydrolase_4" amino acids 73 to 174 (102 residues), 50.5 bits, see alignment E=3.5e-17 amino acids 259 to 309 (51 residues), 31.7 bits, see alignment 2e-11

Best Hits

Swiss-Prot: 83% identical to PRXC_BURPY: Non-heme chloroperoxidase (cpo) from Burkholderia pyrrocinia

KEGG orthology group: K00433, chloride peroxidase [EC: 1.11.1.10] (inferred from 100% identity to atu:Atu4778)

Predicted SEED Role

"Non-heme chloroperoxidase (EC 1.11.1.10)" (EC 1.11.1.10)

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.10

Use Curated BLAST to search for 1.11.1.10

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q7CVU7 at UniProt or InterPro

Protein Sequence (326 amino acids)

>Atu4778 non-heme chloroperoxidase (Agrobacterium fabrum C58)
MTDNPVELAISRRHVLLAGAALSTAMAMPSLAFSKSIPSRNEGTFPMTESFVKNKDGVEI
YFKDWGPKDAQPIVFHHGWPLSSDDWDAQMLFFVQNGYRVVAHDRRGHGRSQQVSDGHDM
DHYAADASAVAEHLDLRNAVHIGHSTGGGEVARYVAKFGQPQGRVAKAVLVSAVPPLMLK
TPSNPGGLPIEVFDSFRKGVAENRAQFFLDVPAGPFYGFNRPDAKIYPGVIRNWWRQGMM
GSAKAHYDGVKAFSETDQTEDLKAITVPTLVLHGDDDQVVPIADSAELSVKLLKNGTLKV
YKGYPHGMLTTHADVINPDLLAFVKG