Protein Info for Atu4760 in Agrobacterium fabrum C58

Annotation: GntR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 482 PF00392: GntR" amino acids 37 to 96 (60 residues), 34.6 bits, see alignment E=1.3e-12 PF00155: Aminotran_1_2" amino acids 124 to 462 (339 residues), 74.9 bits, see alignment E=7.4e-25

Best Hits

KEGG orthology group: None (inferred from 100% identity to atu:Atu4760)

Predicted SEED Role

"Transcriptional regulator GabR of GABA utilization (GntR family with aminotransferase-like domain)" in subsystem Threonine degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A9CH36 at UniProt or InterPro

Protein Sequence (482 amino acids)

>Atu4760 GntR family transcriptional regulator (Agrobacterium fabrum C58)
MRRQANSPSPDPVSTTRPVAWRPTLAKQKGETKHSALTERIIADIDAGVLKPMDRMPTHR
DLARELGLSVQTVSLSYKEAERLGYLSGEIGRGTFVKTRVTERAGRMMLDHSPTEVLDLS
IIRGVYLDDHENASRTILREMADSDNSGFMRPCRPVAGLDSHRETARTWLGMMGVTAGAE
RILVTNGAAHGIFLALSCIIRSNDVVLCENLTDHGIIGLSNILGFSLKGLPTDEEGILPD
ALEAACAAGGVRALVLIPTLNNPTGHVSGAARRQAIATIAERYGIFIIEDEVYRPMIEDD
LPSITEMLPDLGFFVTSFTKTVLTGLRVGYLVVPPAYSIRAASILRVSSWSGTYLTAEIA
TRWVENGTARRLLDVQRTEARARQKIAVDILGDHIGSTHPLSFCAWLTVPPRWTEDGLVR
ALTNQNVAVTPSEPFIAGPGHGGGIRICLGGRLNHASLARALTTVRQTFEQLPPVYDIGS
IG